(R)-(-)-α-甲氧基苯乙酸合成路线 （共 47 条）
反应条件
in methanol 3.5 h; Heating; Yield given. Yields of byproduct given;
参考文献
Touet, Joel; Faveriel, Laurent; Brown, Eric
Tetrahedron, 1995 , vol. 51, # 6 p. 1709 - 1720
参考文献
Mc Kenzie; Wren
Journal of the Chemical Society, 1910 , vol. 97, p. 484,485
参考文献
McKenzie; Walker
Journal of the Chemical Society, 1915 , vol. 107, p. 1696
参考文献
McKenzie; Walker
Journal of the Chemical Society, 1915 , vol. 107, p. 1696
反应条件
lithium aluminium tetrahydride in diethyl ether 2 h; Ambient temperature;
参考文献
Rose, Ulrich; Draeger, Martin
Journal of Medicinal Chemistry, 1992 , vol. 35, # 12 p. 2238 - 2243
反应条件
hydrogenchloride; 4-(N,N-dimethlyamino)pyridine in tetrahydrofuran; dichloromethane
参考文献
Merck and Co. Inc.
Patent: US5010100 A1, 1991 ;
US 5010100 A
反应条件
1: SOCl2 / 24 h / Ambient temperature 2: 1 M NaOH / H2O; CH2Cl2 / 24 h / Ambient temperature 3: 4-(dimethylamino)pyridine / acetonitrile / 48 h / Ambient temperature 4: 1.11 g / 1,1,3,3-tetramethylguanidine / methanol / 1.5 h / Ambient temperature View Scheme
参考文献
Nilsson, Bjoern M.; Hacksell, Uli
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1988 , vol. 42, # 1 p. 55 - 58
