(R)-(-)-α-甲氧基苯乙酸合成路线 （共 47 条）
反应条件
1: Ag2O 2: aq. H2SO4 View Scheme
参考文献
Barth,G. et al.
Journal of the American Chemical Society, 1970 , vol. 92, p. 875 - 886
反应条件
water; Candida rugosa lipase in cyclohexane T=45°C; 9 h; Resolution of racemateEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Wang, Pei-Yun; Wu, Chia-Hui; Ciou, Jyun-Fen; Wu, An-Chi; Tsai, Shau-Wei
Journal of Molecular Catalysis B: Enzymatic, 2010 , vol. 66, # 1-2 p. 113 - 119
反应条件
Candida antarctica lipase B; water in tert-butyl methyl ether T=45°C; 0.8 h; Resolution of racemateEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Wang, Pei-Yun; Wu, Chia-Hui; Ciou, Jyun-Fen; Wu, An-Chi; Tsai, Shau-Wei
Journal of Molecular Catalysis B: Enzymatic, 2010 , vol. 66, # 1-2 p. 113 - 119
反应条件
water; Candida rugosa lipase in cyclohexane T=45°C; 15.4 h; Resolution of racemateEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Wang, Pei-Yun; Wu, Chia-Hui; Ciou, Jyun-Fen; Wu, An-Chi; Tsai, Shau-Wei
Journal of Molecular Catalysis B: Enzymatic, 2010 , vol. 66, # 1-2 p. 113 - 119
反应条件
ammonium hydroxide; sodium hydroxide; silver nitrate in water; toluene T=20°C; optical yield given as percent ee;
参考文献
Singh, Buddh; Gupta, Pankaj; Chaubey, Asha; Parshad, Rajinder; Sharma, Shiromani; Taneja, Subhash C.
Tetrahedron Asymmetry, 2008 , vol. 19, # 22 p. 2579 - 2588
反应条件
ruthenium trichloride; sodium periodate
参考文献
Takeshita; Akutsu
Tetrahedron Asymmetry, 1992 , vol. 3, # 11 p. 1381 - 1384
反应条件
periodic acid; ruthenium trichloride
参考文献
Wei, Han-Xun; Willis, Steven; Li, Guigen
Tetrahedron Letters, 1998 , vol. 39, # 45 p. 8203 - 8206
反应条件
1: Pb(OAc)4 / benzene / 20 °C 2: 95 percent / NaClO2; NaH2PO4 / H2O; 2-methyl-propan-2-ol View Scheme
参考文献
Prasad, Kavirayani R.; Chandrakumar, Appayee
Tetrahedron Asymmetry, 2005 , vol. 16, # 11 p. 1897 - 1900
反应条件
1: FeCl3*6H2O / CH2Cl2 / 20 °C 2: Pb(OAc)4 / benzene / 20 °C 3: 95 percent / NaClO2; NaH2PO4 / H2O; 2-methyl-propan-2-ol View Scheme
参考文献
Prasad, Kavirayani R.; Chandrakumar, Appayee
Tetrahedron Asymmetry, 2005 , vol. 16, # 11 p. 1897 - 1900
反应条件
1.1: K-selectride; 18-crown-6 / tetrahydrofuran / 4.5 h / -78 °C 1.2: NaH / dimethylformamide / 20 °C 2.1: FeCl3*6H2O / CH2Cl2 / 20 °C 3.1: Pb(OAc)4 / benzene / 20 °C 4.1: 95 percent / NaClO2; NaH2PO4 / H2O; 2-methyl-propan-2-ol View Scheme
参考文献
Prasad, Kavirayani R.; Chandrakumar, Appayee
Tetrahedron Asymmetry, 2005 , vol. 16, # 11 p. 1897 - 1900
