3,5-二氯-4-甲基苯甲酸合成路线 (共 13 条)
反应条件
copper(I) oxide in quinoline T=220°C; Autoclave;
参考文献
Mukhopadhyay; Chandalia
Organic Process Research and Development, 1999 , vol. 3, # 1 p. 10 - 16
反应条件
1: 3,5-dichloro-4-methylbenzoic acid With 4-methyl-morpholine; 2-chloro-4,6-dimethoxy-[1,3,5]triazine in tert-butyl methyl ether T=20°C; 1 h; 2: 3-amino-1-chloro-3-methylpentan-2-one hydrochloride in tert-butyl methyl ether T=55°C; 6 h;
参考文献
Rayle, Heather L.; Fellmeth, Lisa
Organic Process Research and Development, 1999 , vol. 3, # 3 p. 172 - 176
反应条件
thionyl chloride in N-methyl-acetamide; toluene
参考文献
Rohm and Haas Company
Patent: US5304572 A1, 1994 ;