2,3-二甲基-2,3-二硝基丁烷合成路线 （共 158 条）
反应条件
1: 79 percent / Al/Hg / tetrahydrofuran; H2O / 0.75 h / -7 - -2 °C
2: 96 percent / p-TsOH*H2O / methanol / 48 h / 20 °C
View Scheme
参考文献
Wu, Yihui; Bi, Lanrong; Bi, Wei; Li, Zeng; Zhao, Ming; Wang, Chao; Ju, Jingfang; Peng, Shiqi
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 16 p. 5711 - 5720
反应条件
1: 63 percent / Zn; NH4Cl / tetrahydrofuran; H2O / 3 h / 10 °C
2: 43 percent / methanol / 16 h / 20 °C
View Scheme
参考文献
Wu, Yihui; Bi, Lanrong; Bi, Wei; Li, Zeng; Zhao, Ming; Wang, Chao; Ju, Jingfang; Peng, Shiqi
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 16 p. 5711 - 5720
反应条件
1: 63 percent / Zn; NH4Cl / tetrahydrofuran; H2O / 3 h / 10 °C
2: 51 percent / methanol / 16 h / 20 °C
View Scheme
参考文献
Shimono, Satoshi; Tamura, Rui; Ikuma, Naohiko; Takimoto, Tatsuya; Kawame, Naoyuki; Tamada, Osamu; Sakai, Naoko; Matsuura, Hiroaki; Yamauchi, Jun
Journal of Organic Chemistry, 2004 , vol. 69, # 2 p. 475 - 481
反应条件
1: 63 percent / Zn; NH4Cl / tetrahydrofuran; H2O / 3 h / 10 °C
2: 57 percent / methanol / 16 h / 20 °C
View Scheme
参考文献
Wu, Yihui; Bi, Lanrong; Bi, Wei; Li, Zeng; Zhao, Ming; Wang, Chao; Ju, Jingfang; Peng, Shiqi
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 16 p. 5711 - 5720
反应条件
1: 63 percent / Zn; NH4Cl / tetrahydrofuran; H2O / 3 h / 10 °C
2: 63 percent / methanol / 16 h / 20 °C
3: 73 percent / lead dioxide / methanol / 0.33 h / 20 °C
View Scheme
参考文献
Hirel, Catherine; Vostrikova, Kira E.; Pecaut, Jacques; Ovcharenko, Victor I.; Rey, Paul
Chemistry - A European Journal, 2001 , vol. 7, # 9 p. 2007 - 2014
反应条件
1.1: 81 percent / Sn; aq. HCl / 3 h / Heating
2.1: 95 percent / diethyl ether / ice cooling
3.1: m-chloroperbenzoic acid; NaHCO3 / CH2Cl2 / 1 h / Ice cooling
3.2: aq. NaIO4 / CH2Cl2
View Scheme
参考文献
Hirel, Catherine; Vostrikova, Kira E.; Pecaut, Jacques; Ovcharenko, Victor I.; Rey, Paul
Chemistry - A European Journal, 2001 , vol. 7, # 9 p. 2007 - 2014
反应条件
1: 63 percent / Zn; NH4Cl / tetrahydrofuran; H2O / 19 h / 4 - 10 °C
2: 69 percent / methanol / 1 h / 20 °C
3: 79 percent / lead dioxide / methanol / 3 h / 20 °C
View Scheme
参考文献
Hirel, Catherine; Vostrikova, Kira E.; Pecaut, Jacques; Ovcharenko, Victor I.; Rey, Paul
Chemistry - A European Journal, 2001 , vol. 7, # 9 p. 2007 - 2014
反应条件
1: 79 percent / Al/Hg / tetrahydrofuran; H2O / 0.75 h / -7 - -2 °C
2: 87 percent / p-TsOH*H2O / methanol / 48 h / 20 °C
View Scheme
参考文献
Wu, Yihui; Bi, Lanrong; Bi, Wei; Li, Zeng; Zhao, Ming; Wang, Chao; Ju, Jingfang; Peng, Shiqi
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 16 p. 5711 - 5720
