sulfuric acid; meta-nitrobenzenesulfonic acid T=140°C; Skraup reaction; Title compound not separated from byproducts;

1: 7-Fluoroquinoline; bromocyane in methanol T=20°C; Addition; 96 h; 2: N-bromoacetamide in methanol T=20°C; Bromination; 24 h; 3: With hydrogenchloride in methanol T=100°C; Hydrolysis; 3 h;

1.1: methanol / 96 h / 20 °C 1.2: methanol / 24 h / 20 °C 1.3: 65 percent / c-HCl / methanol / 3 h / 100 °C 2.1: c-NH3 aq.; CuSO4*5H2O / 20 h / 160 °C View Scheme