环戊烷-1,3-二羧酸二甲酯合成路线 （共 8 条）
反应条件
phosphate buffer in acetonitrile T=37°C; pH 7.0, cholesterol esterase; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Wang, Yi-Fong; Yakovlevsky, Kirill; Zhang, Bailing; Margolin, Alexey L.
Journal of Organic Chemistry, 1997 , vol. 62, # 11 p. 3488 - 3495
反应条件
barium dihydroxide; water
参考文献
Pigou, Paul E.
Journal of Organic Chemistry, 1989 , vol. 54, # 20 p. 4943 - 4950
反应条件
barium dihydroxide; water
参考文献
Pigou, Paul E.
Journal of Organic Chemistry, 1989 , vol. 54, # 20 p. 4943 - 4950
反应条件
1: phosphate buffer / acetonitrile / 37 °C / pH 7.0, cholesterol esterase 2: 82 percent / NH3 / methanol 3: 92 percent / bis(trifluoroacetoxy)iodobenzene / acetonitrile; H2O View Scheme
参考文献
Chenevert; Martin
Tetrahedron Asymmetry, 1992 , vol. 3, # 2 p. 199 - 200
反应条件
1: phosphate buffer / acetonitrile / 37 °C / pH 7.0, cholesterol esterase 2: Et3N / acetone / -5 °C 3: NaN3 / H2O / -5 °C 4: toluene / Heating 5: 80 percent / 8 N aq. HCl / methanol View Scheme
参考文献
Chenevert; Martin
Tetrahedron Asymmetry, 1992 , vol. 3, # 2 p. 199 - 200
反应条件
1: phosphate buffer / acetonitrile / 37 °C / pH 7.0, cholesterol esterase 2: Et3N / acetone / -5 °C 3: NaN3 / H2O / -5 °C 4: toluene / Heating View Scheme
参考文献
Chenevert; Martin
Tetrahedron Asymmetry, 1992 , vol. 3, # 2 p. 199 - 200
反应条件
1: water, Ba(OH)2
2: SOCl2
View Scheme
参考文献
Pigou, Paul E.
Journal of Organic Chemistry, 1989 , vol. 54, # 20 p. 4943 - 4950
反应条件
1: 1.) n-BuLi, diisopropylamine, 2.) HMPA / 1.) THF, -78 deg C, 10 min, 2.) THF, -78 deg C, 2 h
2: 4.4 g / n-BuLi, diisopropylamine, HMPA / tetrahydrofuran / 2.5 h / -78 °C / other substrates, other base
View Scheme
参考文献
Warner, Philip M.; Chen, Bing-Lin; Wada, Eiji
Journal of Organic Chemistry, 1981 , vol. 46, # 23 p. 4795 - 4797
