2-(3-硝基苯亚甲基)乙酰乙酸甲酯合成路线 （共 11 条）
反应条件
piperidine; acetic acid in benzene 4 h; Ambient temperature;
参考文献
Ohno; Komatsu; Mizukoshi; Ichihara; Nakamura; Morishima; Sumita
Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 4 p. 1589 - 1606
反应条件
in ethanol 6 h; Reflux;
参考文献
Zhou, Kai; Wang, Xiao-Meng; Zhao, Yi-Zhi; Cao, Yong-Xiao; Fu, Qiang; Zhang, San-Qi
Medicinal Chemistry Research, 2011 , vol. 20, # 8 p. 1325 - 1330
反应条件
in isopropyl alcohol 10 h; Heating;
参考文献
Meguro; Aizawa; Sohda; Kawamatsu; Nagaoka
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 9 p. 3787 - 3797
反应条件
in methanol; chloroform; ethyl acetate; acetone
参考文献
Yamanouchi Pharmaceutical Co., Ltd.
Patent: US3985758 A1, 1976 ;
反应条件
in methanol; ethanol; chloroform; ethyl acetate; acetone
参考文献
Yamanouchi Pharmaceutical Co., Ltd.
Patent: US3985758 A1, 1976 ;
反应条件
in isopropyl alcohol 10 h; Heating;
参考文献
Meguro; Aizawa; Sohda; Kawamatsu; Nagaoka
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 9 p. 3787 - 3797
参考文献
Meyer; Bossert; Wehinger; Stoepel; Vater
Arzneimittel-Forschung/Drug Research, 1981 , vol. 31, # 3 p. 407 - 409
参考文献
Boehringer Biochemia Robin S.p.A.
Patent: US5047414 A1, 1991 ;
反应条件
in ethanol
4 h; Heating;
参考文献
Ohno; Komatsu; Mizukoshi; Ichihara; Nakamura; Morishima; Sumita
Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 4 p. 1589 - 1606
反应条件
sodium hydroxide in ethanol
T=0°C; Michael Addition;
参考文献
Miao, Chun-Bao; Dong, Chun-Ping; Wang, Yan-Hong; Yang, Hai-Tao; Meng, Qi; Tu, Shu-Jiang; Sun, Xiao-Qiang
Heterocycles, 2013 , vol. 87, # 4 p. 853 - 859
