2-氧代-3-甲基丁酸甲酯合成路线 （共 25 条）
反应条件
lead(IV) acetate in dichloromethane
参考文献
Zbiral,E.; Werner,E.
Monatshefte fuer Chemie, 1966 , vol. 97, p. 1797 - 1820
反应条件
1: tert-butyl hypochlorite / diethyl ether / 0.5 h / 0 °C 2: sodium ethoxide / ethanol / 1 h / 40 °C 3: 5percent sulfuric acid / H2O / 2 h / Ambient temperature View Scheme
参考文献
Ikota; Achiwa; Yamada
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 3 p. 887 - 894
反应条件
1: sodium ethoxide / ethanol / 1 h / 40 °C 2: 5percent sulfuric acid / H2O / 2 h / Ambient temperature View Scheme
参考文献
Ikota; Achiwa; Yamada
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 3 p. 887 - 894
反应条件
sulfuric acid in tetrahydrofuran; diethyl ether Heating;
参考文献
Poisel,H.
Chemische Berichte, 1978 , vol. 111, p. 3136 - 3139
反应条件
1: (i) tBuOCl, (ii) /BRN= 3592982/ 2: aq. H2SO4 / diethyl ether; tetrahydrofuran / Heating View Scheme
参考文献
Poisel,H.
Chemische Berichte, 1978 , vol. 111, p. 3136 - 3139
反应条件
sulfuric acid in water 2 h; Ambient temperature; Yield given;
参考文献
Ikota; Achiwa; Yamada
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 3 p. 887 - 894
反应条件
sulfuric acid 20 h; Heating;
参考文献
Fennie, Michael W.; DiMauro, Erin F.; O'Brien, Erin M.; Annamalai, Venkatachalam; Kozlowski, Marisa C.
Tetrahedron, 2005 , vol. 61, # 26 p. 6249 - 6265
反应条件
hydrogenchloride; diethylamino-sulfur trifluoride 1.) dichlorometane, room temp., 1 h, 2.) 8 h; Yield given. Multistep reaction;
参考文献
Groth, Ulrich; Schoellkopf, Ulrich
Synthesis, 1983 , # 8 p. 673 - 675
反应条件
thionyl chloride 0.5 h;
参考文献
Bendall, Justin G.; Cambie, Richard C.; Moratti, Stephen C.; Rutledge, Peter S.; Woodgate, Paul D.
Australian Journal of Chemistry, 1995 , vol. 48, # 10 p. 1747 - 1756
反应条件
tetrafluoroboric acid; hydrogen; [Ru(R)-Binap(benzene)Cl]Cl in methanol T=30°C; P=76000 Torr; 70 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Mashima, Kazushi; Kusano, Koh-hei; Sato, Naomasa; Matsumura, Yoh-ichi; Nozaki, Kyoko; et al.
Journal of Organic Chemistry, 1994 , vol. 59, # 11 p. 3064 - 3076
