3,4-二羟基苯甲酸乙酯合成路线 （共 47 条）
反应条件
1: K2CO3 / butan-2-one / 84 h / Heating 2: KOH / ethanol / 2.5 h / Heating View Scheme
参考文献
Journal of Materials Chemistry, , vol. 8, # 2 p. 331 - 341
反应条件
potassium carbonate in acetonitrile T=55°C; 16 h;
参考文献
AUSPEX PHARMACEUTICALS, INC.
Patent: US2010/75916 A1, 2010 ;
Location in patent: Page/Page column 17 ;
US 20100075916 A1
反应条件
potassium carbonate; potassium iodide in acetonitrile T=40°C;
参考文献
Qian, Changgeng; Cai, Xiong; Zhai, Haixiao
Patent: US2009/76044 A1, 2009 ;
Location in patent: Page/Page column 30 ;
US 20090076044 A1
反应条件
potassium carbonate in butanone T=100°C; 3 h;
参考文献
Shah, Ajit; Font, Jose L.; Miller, Michael J.; Ream, Joel E.; Walker, Mark C.; Sikorski, James A.
Bioorganic and Medicinal Chemistry, 1997 , vol. 5, # 2 p. 323 - 334
反应条件
potassium carbonate in acetone 16 h; Heating;
参考文献
Salituro; Demeter; Weintraub; Lippert; Resvick; McDonald
Journal of Medicinal Chemistry, 1994 , vol. 37, # 24 p. 4076 - 4078
反应条件
1.1: potassium tert-butylate / N,N-dimethyl-formamide / 0.17 h / Inert atmosphere 1.2: 0.17 h / Inert atmosphere 2.1: potassium carbonate / N,N-dimethyl-formamide / 0.5 h / 20 °C / Inert atmosphere; Cooling with ice 3.1: potassium carbonate / methanol / 2 h / Inert atmosphere; Reflux View Scheme
参考文献
Zhang, Qingzhi; Raheem, K. Saki; Botting, Nigel P.; Slawin, Alexandra M.Z.; Kay, Colin D.; O'Hagan, David
Tetrahedron, 2012 , vol. 68, # 22 p. 4194 - 4201
反应条件
potassium hydroxide in methanol; water; butanone
参考文献
E. I. Du Pont de Nemours and Company
Patent: US4798892 A1, 1989 ;
反应条件
1: K2CO3*1.5H2O / acetone / 24 h / Heating 2: 1.93 g / NaOH / H2O; methanol / 3 h / Heating View Scheme
参考文献
Gardner, Richard Andrew; Kinkade, Rebecca; Wang, Chaojie; Phanstiel IV, Otto
Journal of Organic Chemistry, 2004 , vol. 69, # 10 p. 3530 - 3537
反应条件
potassium carbonate in acetone T=20°C; 9 h;
参考文献
Verma, Alok K.; Singh, Himanshu; Satyanarayana, Mavurapu; Srivastava, Swayam P.; Tiwari, Priti; Singh, Amar B.; Dwivedi, Anil K.; Singh, Shio K.; Srivastava, Mukesh; Nath, Chandishwar; Raghubir, Ram; Srivastava, Arvind K.; Pratap, Ram
Journal of Medicinal Chemistry, 2012 , vol. 55, # 10 p. 4551 - 4567
反应条件
potassium carbonate in butanone T=100°C; 3 h;
参考文献
Shah, Ajit; Font, Jose L.; Miller, Michael J.; Ream, Joel E.; Walker, Mark C.; Sikorski, James A.
Bioorganic and Medicinal Chemistry, 1997 , vol. 5, # 2 p. 323 - 334
