2-氟烟酸合成路线

参考文献

AMGEN INC.
Patent: WO2007/48070 A2, 2007 ;
Location in patent: Page/Page column 117 ;

124-38-9二氧化碳

393-55-52-氟烟酸

参考文献

AMGEN INC.
Patent: WO2006/12374 A1, 2006 ;
Location in patent: Page/Page column 149-150 ;
WO 2006/012374 A1

372-48-52-氟吡啶

393-55-52-氟烟酸

参考文献

Shi, Guo-qiang; Takagishi, Sadahito; Schlosser, Manfred
Tetrahedron, 1994 , vol. 50, # 4 p. 1129 - 1134

2369-18-82-氟-3-甲基吡啶

393-55-52-氟烟酸

参考文献

Timperley, Christopher M.; Banks, R. Eric; Young, Ian M.; Haszeldine, Robert N.
Journal of Fluorine Chemistry, 2011 , vol. 132, # 8 p. 541 - 547

1603-40-32-氨基-3-甲基吡啶

393-55-52-氟烟酸

参考文献

Timperley, Christopher M.; Banks, R. Eric; Young, Ian M.; Haszeldine, Robert N.
Journal of Fluorine Chemistry, 2011 , vol. 132, # 8 p. 541 - 547

5345-47-12-氨基烟酸

393-55-52-氟烟酸

参考文献

Beaty; Musgrave
Journal of the Chemical Society, 1951 , p. 3512

393-55-52-氟烟酸

364-22-72-氟烟酰胺

参考文献

ELI LILLY AND COMPANY
Patent: WO2005/66126 A1, 2005 ;
Location in patent: Page/Page column 61 ;
WO 2005/066126 A1

393-55-52-氟烟酸

36404-90-72-氟烟醛

参考文献

Ashimori; Ono; Uchida; Ohtaki; Fukaya; Watanabe; Yokoyama
Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 9 p. 2446 - 2458

67-56-1甲醇+

393-55-52-氟烟酸

446-26-42-氟烟酸甲酯

参考文献

Beaty; Musgrave
Journal of the Chemical Society, 1951 , p. 3512

393-55-52-氟烟酸

609-71-22-羟基烟酸

参考文献

SK BIOPHARMACEUTICALS CO., LTD.; Maeng, Cheol Young; Jang, Young Koo; Cha, Su Bong; Shin, Hye Won; Joung, Chan Mi; Cha, Hwa Ryun; Yi, Eun Jung
Patent: US2013/317059 A1, 2013 ;
Location in patent: Paragraph 0403 ;