2-三氟甲基-4-氨基苯甲酸合成路线 （共 3 条）
反应条件
iron; ammonium chloride
参考文献
Hauptschein et al.
Journal of the American Chemical Society, 1954 , vol. 76, p. 1051,1054
反应条件
1: aqueous H2SO4 / 182 °C 2: iron; aqueous NH4Cl View Scheme
参考文献
Hauptschein et al.
Journal of the American Chemical Society, 1954 , vol. 76, p. 1051,1054
反应条件
1: With hydrogenchloride; sodium nitrite in water
T=0°C; 0.333333 h;
2: With potassium iodide in water
T=0 - 20°C;
参考文献
GLAXO GROUP LIMITED; ALLEN, David, George; COE, Diane, Mary; COOPER, Anthony, William, James; GORE, Paul, Martin; HOUSE, David; SENGER, Stefan; SOLLIS, Steven, Leslie; VILE, Sadie; WILSON, Caroline
Patent: WO2010/122089 A1, 2010 ;
Location in patent: Page/Page column 61 ;
