2-氯-3,5-二硝基三氟甲苯合成路线 （共 14 条）
反应条件
sulfuric acid; nitric acid T=75 - 130°C;
参考文献
Rasheed,K.; Warkentin,J.D.
Journal of Organic Chemistry, 1979 , vol. 44, p. 267 - 274
参考文献
du Pont de Nemours and Co.
Patent: US2257093 , 1937 ;
参考文献
Endeshaw, Molla M.; Li, Catherine; Leon, Jessica De; Yao, Ni; Latibeaudiere, Kirk; Premalatha, Kokku; Morrissette, Naomi; Werbovetz, Karl A.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 17 p. 5179 - 5183
参考文献
AT339089DE2509416 , ;
Chem.Abstr., , vol. 84, # 30639
参考文献
Du Pont de Nemours and Co.
Patent: US2212825 , 1937 ;
参考文献
Eli Lilly and Company
Patent: US4407820 A1, 1983 ;
参考文献
Du Pont de Nemours and Co.
Patent: US2194925 , 1937 ;
反应条件
sodium hydride in N,N-dimethyl-formamide
参考文献
Imperial Chemical Industries Limited
Patent: US4117167 A1, 1978 ;
反应条件
potassium hydroxide in N-methyl-acetamide
参考文献
Imperial Chemical Industries Limited
Patent: US4128665 A1, 1978 ;
反应条件
1: 94 percent / acetone
2: 33 percent / acetic acid / 3 h / 120 - 125 °C
View Scheme
参考文献
Rasheed, Khalid; Warkentin, James D.
Journal of Organic Chemistry, 1980 , vol. 45, # 20 p. 4041 - 4044
