3-(3-吲哚基)-2-氧代丙酸合成路线 （共 41 条）
反应条件
ammonium sulfate in phosphate buffer T=30°C; pH=8; 1.5 h; Enzymatic reaction;
参考文献
Asamizu, Shumpei; Kato, Yasuo; Igarashi, Yasuhiro; Onaka, Hiroyasu
Tetrahedron Letters, 2007 , vol. 48, # 16 p. 2923 - 2926
反应条件
in water Irradiation;
参考文献
Saito, Isao; Sugiyama, Hiroshi; Matsuura, Teruo; Fukuyama, Keiichi; Katsube, Yukiteru
Tetrahedron Letters, 1984 , vol. 25, # 30 p. 3243 - 3246
反应条件
ethylenediaminetetraacetic acid in methanol T=20°C; pH=7.5; aq. buffer;
参考文献
Skouta, Rachid; Wei, Sujun; Breslow, Ronald
Journal of the American Chemical Society, 2009 , vol. 131, # 43 p. 15604 - 15605
反应条件
Pyridoxamine; β-cyclodextrin pH 8, other reagent;
参考文献
Liu, Lei; Rozenman, Mary; Breslow, Ronald
Journal of the American Chemical Society, 2002 , vol. 124, # 43 p. 12660 - 12661
反应条件
1.1: 76 percent / methanol; diethyl ether / 3 h / 20 °C
2.1: sodium methoxide / methanol / 1 h / 20 °C
2.2: I2 / methanol / 0.5 h / 20 °C
2.3: 37 percent / aq. NH3 / methanol / 1 h / Heating
View Scheme
参考文献
Nishizawa, Tomoyasu; Grueschow, Sabine; Jayamaha, Don-Hema E.; Nishizawa-Harada, Chizuko; Sherman, David H.
Journal of the American Chemical Society, 2006 , vol. 128, # 3 p. 724 - 725
反应条件
in methanol; diethyl ether
T=20°C; 3 h;
参考文献
Nishizawa, Tomoyasu; Grueschow, Sabine; Jayamaha, Don-Hema E.; Nishizawa-Harada, Chizuko; Sherman, David H.
Journal of the American Chemical Society, 2006 , vol. 128, # 3 p. 724 - 725
参考文献
Bentley et al.
Biochemical Journal, 1956 , vol. 64, p. 44,45
反应条件
1: With sodium hydroxide in water
T=35°C; Aldol Condensation; pH=11.0 - 11.1; 6.5 - 16 h;
2: With hydrogenchloride in water
pH=6.91; Product distribution / selectivity;
参考文献
Ajinomoto Co., Inc.
Patent: EP1719758 A1, 2006 ;
Location in patent: Page/Page column 3; 7 ;
反应条件
sodium hydroxide; sodium carbonate in water
T=20°C; pH=12.4; 2 h;
参考文献
Ajinomoto Co., Inc.
Patent: EP1719758 A1, 2006 ;
Location in patent: Page/Page column 3; 8 ;
反应条件
1: With potassium hydroxide in water
T=35°C; 24 h;
2: With hydrogenchloride in water
pH=7.0; Product distribution / selectivity;
参考文献
Ajinomoto Co., Inc.
Patent: US7297800 B2, 2007 ;
Location in patent: Page/Page column 41-42 ;
