4-氟水杨酸甲酯合成路线

345-29-94-氟水杨酸

392-04-14-氟水杨酸甲酯

参考文献

WYETH
Patent: WO2005/12291 A1, 2005 ;
Location in patent: Page/Page column 72 ;
WO 2005/012291 A1

345-29-94-氟水杨酸+

18107-18-1三甲基硅烷化重氮甲烷

392-04-14-氟水杨酸甲酯

参考文献

ELI LILLY AND COMPANY
Patent: WO2005/49604 A2, 2005 ;
Location in patent: Page/Page column 40 ;
WO 2005/049604 A2

345-29-94-氟水杨酸+

74-88-4甲基碘

392-04-14-氟水杨酸甲酯

参考文献

Buchstaller, Hans-Peter; Eggenweiler, Hans-Michael; Sirrenberg, Christian; Graedler, Ulrich; Musil, Djordje; Hoppe, Edmund; Zimmermann, Astrid; Schwartz, Harry; Maerz, Joachim; Bomke, Joerg; Wegener, Ansgar; Wolf, Michael
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 13 p. 4396 - 4403

67-56-1甲醇+

345-29-94-氟水杨酸

392-04-14-氟水杨酸甲酯

参考文献

Watanuki, Susumu; Matsuura, Keisuke; Tomura, Yuichi; Okada, Minoru; Okazaki, Toshio; Ohta, Mitsuaki; Tsukamoto, Shin-Ichi
Chemical and Pharmaceutical Bulletin, 2012 , vol. 60, # 2 p. 223 - 234

455-68-53-氟苯甲酸甲酯

391-92-45-氟-2-羟基苯甲酸甲酯+

392-04-14-氟水杨酸甲酯+

456-47-33-氟苄醇

参考文献

Boyd, Derek R.; Sharma, Narain D.; Harrison, John S.; Malone, John. F.; McRoberts, W. Colin; Hamilton, John T. G.; Harper, David B.
Organic and Biomolecular Chemistry, 2008 , vol. 6, # 7 p. 1251 - 1259

403-33-8对氟苯甲酸甲酯

459-56-3对氟苯甲醇+

391-92-45-氟-2-羟基苯甲酸甲酯+

392-04-14-氟水杨酸甲酯

参考文献

Boyd, Derek R.; Sharma, Narain D.; Harrison, John S.; Malone, John. F.; McRoberts, W. Colin; Hamilton, John T. G.; Harper, David B.
Organic and Biomolecular Chemistry, 2008 , vol. 6, # 7 p. 1251 - 1259

1583-58-02,4-二氟苯甲酸

392-04-14-氟水杨酸甲酯

参考文献

SYNTA PHARMACEUTICALS CORP.; CHIMMANAMADA, Dinesh; DEMKO, Zachary; YING, Weiwen
Patent: WO2013/148857 A1, 2013 ;

392-04-14-氟水杨酸甲酯

345-29-94-氟水杨酸

参考文献

Anderson, Marc O.; Moser, Jamie; Sherrill, John; Guy, R. Kiplin
Synlett, 2004 , # 13 p. 2391 - 2393

392-04-14-氟水杨酸甲酯

1643-78-3

参考文献

Ferraris, Dana; Duvall, Bridget; Ko, Yao-Sen; Thomas, Ajit G.; Rojas, Camilo; Majer, Pavel; Hashimoto, Kenji; Tsukamoto, Takashi
Journal of Medicinal Chemistry, 2008 , vol. 51, # 12 p. 3357 - 3359

392-04-14-氟水杨酸甲酯+

74-88-4甲基碘

204707-42-64-氟-2-甲氧基苯甲酸甲酯

参考文献

Schering Corporation
Patent: US2005/239795 A1, 2005 ;
Location in patent: Page/Page column 30 ;
US 20050239795 A1