甲基 2-脱氧-2-氟-beta-D-吡喃葡萄糖苷合成路线 （共 9 条）
反应条件
sodium methylate
T=25°C;
参考文献
Baer; Hernandez Mateo; Siemsen
Carbohydrate research, 1990 , vol. 195, # 2 p. 225 - 245
反应条件
methanesulfonic acid in water
0.5 h; Heating;
参考文献
Haradahira; Maeda; Kai; et al.
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 1 p. 165 - 172
反应条件
hydrogen; palladium on activated charcoal
参考文献
Kovac; Yeh; Glaudemans
Carbohydrate research, 1987 , vol. 169, p. 23 - 34
反应条件
1: 90 percent / 45percent HBr / CHCl3; acetic acid / 3 h / 25 °C
2: Bu4NBr, ethyldiisopropylamine / CH2Cl2 / 48 h / 55 °C / molecular sieve 4A
3: 98 percent / 0.025M NaOCH3 / 25 °C
View Scheme
参考文献
Baer; Hernandez Mateo; Siemsen
Carbohydrate research, 1990 , vol. 195, # 2 p. 225 - 245
反应条件
1: Bu4NBr, ethyldiisopropylamine / CH2Cl2 / 48 h / 55 °C / molecular sieve 4A
2: 98 percent / 0.025M NaOCH3 / 25 °C
View Scheme
参考文献
Baer; Hernandez Mateo; Siemsen
Carbohydrate research, 1990 , vol. 195, # 2 p. 225 - 245
反应条件
acetyl chloride in methanol; benzene
24 h; Heating;
参考文献
Kovac; Yeh; Glaudemans
Carbohydrate research, 1987 , vol. 169, p. 23 - 34
反应条件
1: 79 percent / pyridine / 1.33 h / 0 °C
2: 57 percent / Et4NF / acetonitrile / 0.33 h / 50 °C / various fluorides, temp.
3: 18 percent / methanesulfonic acid / H2O / 0.5 h / Heating
View Scheme
参考文献
Haradahira; Maeda; Kai; et al.
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 1 p. 165 - 172
反应条件
1: 57 percent / Et4NF / acetonitrile / 0.33 h / 50 °C / various fluorides, temp.
2: 18 percent / methanesulfonic acid / H2O / 0.5 h / Heating
View Scheme
参考文献
Haradahira; Maeda; Kai; et al.
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 1 p. 165 - 172
反应条件
hydrogenchloride in methanol
24 h; Ambient temperature;
参考文献
Kovac; Yeh; Glaudemans
Carbohydrate research, 1987 , vol. 169, p. 23 - 34
