N,N-二乙基-2-羟基乙酰胺合成路线 （共 9 条）
反应条件
hydrogen; palladium 10 on activated carbon in ethyl acetate 24 h;
参考文献
BAYER CROPSCIENCE AG
Patent: US2011/207605 A1, 2011 ;
Location in patent: Page/Page column 9 ;
反应条件
1: sodium acetate / 16 h / Heating 2: sodium methoxide / methanol / 3 h View Scheme
参考文献
Institute of Organic Chemistry and Biochemistry of the Academy of Sciences of the Czech Republic; Rega Stichting v.z.w.
Patent: US5663159 A1, 1997 ;
参考文献
Starrett, John E.; Tortolani, David R.; Russell, John; Hitchcock, Michael J. M.; Whiterock, Valerie; et al.
Journal of Medicinal Chemistry, 1994 , vol. 37, # 12 p. 1857 - 1864
反应条件
in toluene 14 h; Heating;
参考文献
Boyko, Vyacheslav I.; Rodik, Roman V.; Severenchuk, Inna N.; Voitenko, Zoya V.; Kalchenko, Vitaly I.
Synthesis, 2007 , # 14 p. 2095 - 2096
反应条件
malonic acid in diethyl ether 2 h; Heating; Yield given;
参考文献
Ricci, Alfredo; Romanelli, M. Novella; Taddei, Maurizio; Seconi, Giancarlo; Shanzer, Abraham
Synthesis, 1983 , # 4 p. 319 - 322
反应条件
4-(N,N-dimethlyamino)pyridine; methyl propen-2-yl ether 1.) 45 deg C, 30 min, 2.) 55 deg C, 18 h; Yield given. Multistep reaction;
参考文献
Maligres; Weissman; Upadhyay; Cianciosi; Reamer; Purick; Sager; Rossen; Eng; Askin; Volante; Reider
Tetrahedron, 1996 , vol. 52, # 9 p. 3327 - 3338
反应条件
potassium chloride in phosphate buffer; acetonitrile T=37°C; pH=7.4; 0.266667 h; Enzymatic reaction; Kinetics;
参考文献
Talath, Sirajunisa; Shirote, Pramod J.; Lough, W. John; Gadad, Andanappa K.
Arzneimittel-Forschung/Drug Research, 2006 , vol. 56, # 9 p. 631 - 639
参考文献
Andreas,F. et al.
Journal fuer Praktische Chemie (Leipzig), 1962 , vol. 18, p. 141 - 149
反应条件
sodium hydroxide in benzene
参考文献
Mandel'baum,Ya.A. et al.
J. Gen. Chem. USSR (Engl. Transl.), 1963 , vol. 33, p. 3819 - 3822,3757 - 3760
