2-[[4-羟基-3-(三氟甲基)苯基]氨基]苯甲酸合成路线 （共 5 条）
反应条件
hydrogen; palladium on activated charcoal in methanol
参考文献
Boltze; Backer; Kreisfeld
Arzneimittel-Forschung/Drug Research, 1982 , vol. 32, # 3 p. 183 - 186
反应条件
1: 98.8 percent / H2 / Pt
2: 66 percent / K2CO3 / Cu powder / 2 h / 160 °C
3: 87 percent / H2 / 10percent Pd/C / methanol
View Scheme
参考文献
Boltze; Backer; Kreisfeld
Arzneimittel-Forschung/Drug Research, 1982 , vol. 32, # 3 p. 183 - 186
反应条件
1: 92 percent / benzyltributylammonium bromide, NaOH / 24 h / 55 °C
2: 98.8 percent / H2 / Pt
3: 66 percent / K2CO3 / Cu powder / 2 h / 160 °C
4: 87 percent / H2 / 10percent Pd/C / methanol
View Scheme
参考文献
Boltze; Backer; Kreisfeld
Arzneimittel-Forschung/Drug Research, 1982 , vol. 32, # 3 p. 183 - 186
反应条件
1: 66 percent / K2CO3 / Cu powder / 2 h / 160 °C
2: 87 percent / H2 / 10percent Pd/C / methanol
View Scheme
参考文献
Boltze; Backer; Kreisfeld
Arzneimittel-Forschung/Drug Research, 1982 , vol. 32, # 3 p. 183 - 186
反应条件
1: K2CO3, CuBr2, N-ethylmorpholine / bis-(2-methoxy-ethyl) ether
2: H2 / Pd-C
View Scheme
参考文献
Bowman,R.E. et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1973 , p. 1 - 4
