4,5‘,8-三甲基]补骨脂素合成路线 （共 16 条）
反应条件
N,N-diethylaniline T=225°C; 24 h;
参考文献
Kaufman, Kurt D.; Hewitt, Larry E.
Journal of Organic Chemistry, 1980 , vol. 45, # 4 p. 738 - 740
反应条件
1: potassium carbonate / acetone 2: N,N-diethylaniline / 218 °C 3: 2,3-dichloro-5,6-dicyanobenzoquinone (DDQ) / benzene / 12 h / Heating View Scheme
参考文献
Kaufman, Kurt D.; Hewitt, Larry E.
Journal of Organic Chemistry, 1980 , vol. 45, # 4 p. 738 - 740
反应条件
N,N-diethylaniline T=220 - 225°C; 24 h;
参考文献
Kaufman, Kurt D.; Hewitt, Larry E.
Journal of Organic Chemistry, 1980 , vol. 45, # 4 p. 738 - 740
反应条件
1: N,N-diethylaniline / 218 °C 2: 2,3-dichloro-5,6-dicyanobenzoquinone (DDQ) / benzene / 12 h / Heating View Scheme
参考文献
Prashant, Avula; Krupadanam, Gazula Levi David; Srimannarayana, Gutely
Bulletin of the Chemical Society of Japan, 1992 , vol. 65, # 4 p. 1191 - 1193
反应条件
2,3-dicyano-5,6-dichloro-p-benzoquinone in benzene 12 h; Heating; Yield given. Yields of byproduct given;
参考文献
Prashant, Avula; Krupadanam, Gazula Levi David; Srimannarayana, Gutely
Bulletin of the Chemical Society of Japan, 1992 , vol. 65, # 4 p. 1191 - 1193
反应条件
T=15°C; Irradiation; Quantum yield;
参考文献
Journal of Organic Chemistry, , vol. 54, # 17 p. 4125 - 4134
参考文献
Cerus Corporation
Patent: US5593823 A1, 1997 ;
反应条件
palladium on activated charcoal in ethanol
0.5 h; Heating;
参考文献
Heindel; Foster; Choudhuri
Journal of Organic Chemistry, 1983 , vol. 48, # 21 p. 3817 - 3819
反应条件
cyclohexene; palladium on activated charcoal in ethanol
3 h; Heating;
参考文献
Heindel; Van Dongen; Sachais; Phillips; Gallo; Laskin
Journal of Pharmaceutical Sciences, 1991 , vol. 80, # 7 p. 686 - 689
反应条件
hydrogenchloride in water
T=25°C; 12 h;
参考文献
Militsopoulou, Maria; Bariamis, Stavros E.; Athanassopoulos, Constantinos M.; Papaioannou, Dionissios
Synthesis, 2008 , # 21 art. no. T08808SS, p. 3433 - 3442
