N-(2-羟基-苯基)-4-甲基-苯磺酰胺合成路线 （共 18 条）
反应条件
1: 85 percent / sulfuryl chloride, triethylamine / CH2Cl2 / 1) -78 deg C, 15 min, 2) -78 deg C to 5 deg C 2: 78 percent / diethyl ether; hexane; tetrahydrofuran / 0.67 h View Scheme
参考文献
Andersen, Kenneth K.; Bray, Diana D.; Chumpradit, Sumalee; Clark, Michael E.; Habgood, Gregory J.; et al.
Journal of Organic Chemistry, 1991 , vol. 56, # 23 p. 6508 - 6516
反应条件
in neutraler Loesung;
参考文献
Troeger; Ullmann
Journal fuer Praktische Chemie (Leipzig), 1895 , vol. <2>51, p. 441
反应条件
1: 72 percent / K2CO3 / acetone / 24 h / Heating 2: 10percent NaOH / 16 h / Heating View Scheme
参考文献
Bartsch, Herbert; Schwarz, Otto
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 45 - 48
反应条件
1: 85 percent / sulfuryl chloride, triethylamine / CH2Cl2 / 1) -78 deg C, 15 min, 2) -78 deg C to 5 deg C 2: 49 percent / tetrahydrofuran / 0.25 h / Ambient temperature View Scheme
参考文献
Andersen, Kenneth K.; Bray, Diana D.; Chumpradit, Sumalee; Clark, Michael E.; Habgood, Gregory J.; et al.
Journal of Organic Chemistry, 1991 , vol. 56, # 23 p. 6508 - 6516
反应条件
1: 85 percent / sulfuryl chloride, triethylamine / CH2Cl2 / 1) -78 deg C, 15 min, 2) -78 deg C to 5 deg C 2: 93 percent / KF / H2O; acetonitrile View Scheme
参考文献
Andersen, Kenneth K.; Bray, Diana D.; Chumpradit, Sumalee; Clark, Michael E.; Habgood, Gregory J.; et al.
Journal of Organic Chemistry, 1991 , vol. 56, # 23 p. 6508 - 6516
反应条件
1: With magnesium in methanol
T=20°C; 8 h;
2: With hydrogenchloride in water
参考文献
Morgans, Garreth L.; Ngidi, E. Lindani; Madeley, Lee G.; Khanye, Setshaba D.; Michael, Joseph P.; de Koning, Charles B.; van Otterlo, Willem A.L.
Tetrahedron, 2009 , vol. 65, # 51 p. 10650 - 10659
反应条件
pyridine in dichloromethane
1 h; Ambient temperature;
参考文献
Andersen, Kenneth K.; Gowda, Gopala; Jewell, Linda; McGraw, Phillip; Phillips, Brian T.
Journal of Organic Chemistry, 1982 , vol. 47, # 10 p. 1884 - 1889
反应条件
methyllithium in tetrahydrofuran
T=0°C; var. solvents and bases; other 2-aminoaryl arenesulfonates; Product distributionMechanism;
参考文献
Andersen, Kenneth K.; Gowda, Gopala; Jewell, Linda; McGraw, Phillip; Phillips, Brian T.
Journal of Organic Chemistry, 1982 , vol. 47, # 10 p. 1884 - 1889
反应条件
n-butyllithium in diethyl ether; hexane
1 h; Ambient temperature;
参考文献
Andersen, Kenneth K.; Gowda, Gopala; Jewell, Linda; McGraw, Phillip; Phillips, Brian T.
Journal of Organic Chemistry, 1982 , vol. 47, # 10 p. 1884 - 1889
反应条件
1: 94 percent / Et3N / CH2Cl2 / 1 h / Ambient temperature
2: 95 percent / n-BuLi / diethyl ether; hexane / 1 h / Ambient temperature
View Scheme
参考文献
Andersen, Kenneth K.; Gowda, Gopala; Jewell, Linda; McGraw, Phillip; Phillips, Brian T.
Journal of Organic Chemistry, 1982 , vol. 47, # 10 p. 1884 - 1889
