1: potassium hydroxide / tetrahydrofuran; methanol / 1 h / 50 °C / Inert atmosphere 2: immobilized lipase Pseudomonas cepacia / ethyl acetate / 20 h / 20 °C / Inert atmosphere; Enzymatic reaction 3: potassium hydroxide / methanol; dichloromethane / 2 h / 0 °C 4: tetrahydrofuran; toluene / 1.5 h / -20 °C / Inert atmosphere 5: methanol; water / 0 - 20 °C 6: (+/-)-2-Ethyloxirane / ethanol / 6 h / Inert atmosphere; Reflux View Scheme

1: potassium hydroxide / tetrahydrofuran; methanol / 1 h / 50 °C / Inert atmosphere 2: immobilized lipase Pseudomonas cepacia / ethyl acetate / 20 h / 20 °C / Inert atmosphere; Enzymatic reaction 3: tetrahydrofuran; toluene / 1.5 h / -20 °C / Inert atmosphere 4: methanol; water / 0 - 20 °C 5: (+/-)-2-Ethyloxirane / ethanol / 6 h / Inert atmosphere; Reflux View Scheme

1: toluene-4-sulfonic acid; trimethyl orthoformate / hexane / 20 °C / Inert atmosphere 2: potassium carbonate; tert.-butylhydroperoxide; sodium hypochlorite / acetonitrile; water / 9.5 h / -5 - 0 °C / Inert atmosphere; Cooling with ice-salt 3: hydrogenchloride / water; acetone / 3.16 h / 20 °C / Inert atmosphere View Scheme

1: potassium carbonate; tert.-butylhydroperoxide; sodium hypochlorite / acetonitrile; water / 9.5 h / -5 - 0 °C / Inert atmosphere; Cooling with ice-salt 2: hydrogenchloride / water; acetone / 3.16 h / 20 °C / Inert atmosphere View Scheme