1-(4-甲氧基苯基)-6-苯基己三烯合成路线 （共 11 条）
反应条件
iodine in benzene Irradiation;
参考文献
Leznoff,C.C.; Hayward,R.J.
Canadian Journal of Chemistry, 1972 , vol. 50, p. 528 - 533
反应条件
bis-triphenylphosphine-palladium(II) chloride; triethylamine in tetrahydrofuran
T=20°C;
参考文献
Crousse, Benoit; Mladenova, Margarita; Ducept, Pascal; Alami, Mouad; Linstrumelle, Gerard
Tetrahedron, 1999 , vol. 55, # 14 p. 4353 - 4368
反应条件
bis-triphenylphosphine-palladium(II) chloride; triethylamine in tetrahydrofuran
4 h;
参考文献
Crousse, Benoit; Mladenova, Margarita; Ducept, Pascal; Alami, Mouad; Linstrumelle, Gerard
Tetrahedron, 1999 , vol. 55, # 14 p. 4353 - 4368
反应条件
1: 1.) methanesulfonyl chloride, triethylamine, 2.) DBU / 1.) CH2Cl2, room temperature, 30 min, 2.) CH2Cl2, room temperature
2: 82 percent / PdCl2(PPh3)2, triethylamine / tetrahydrofuran / 4 h
View Scheme
参考文献
Crousse, Benoit; Mladenova, Margarita; Ducept, Pascal; Alami, Mouad; Linstrumelle, Gerard
Tetrahedron, 1999 , vol. 55, # 14 p. 4353 - 4368
反应条件
1: 62 percent / Red-Al / diethyl ether; toluene / 5 h / -20 - 36 °C
2: 1.) methanesulfonyl chloride, triethylamine, 2.) DBU / 1.) CH2Cl2, room temperature, 30 min, 2.) CH2Cl2, room temperature
3: 82 percent / PdCl2(PPh3)2, triethylamine / tetrahydrofuran / 4 h
View Scheme
参考文献
Crousse, Benoit; Mladenova, Margarita; Ducept, Pascal; Alami, Mouad; Linstrumelle, Gerard
Tetrahedron, 1999 , vol. 55, # 14 p. 4353 - 4368
反应条件
1: 82 percent / PdCl2(PPh3)2, CuI, piperidine / diethyl ether / 4 h / 15 - 20 °C
2: 79 percent / Red-Al / diethyl ether; toluene / 5 h / -20 - 36 °C
3: 1.) methanesulfonyl chloride, triethylamine, 2.) DBU / 1.) CH2Cl2, room temperature, 30 min, 2.) CH2Cl2, room temperature
4: 78 percent / PdCl2(PPh3)2, triethylamine / tetrahydrofuran / 4 h
View Scheme
参考文献
Crousse, Benoit; Mladenova, Margarita; Ducept, Pascal; Alami, Mouad; Linstrumelle, Gerard
Tetrahedron, 1999 , vol. 55, # 14 p. 4353 - 4368
反应条件
1: 89 percent / PdCl2(PPh3)2, CuI, piperidine / diethyl ether / 4 h / 15 - 20 °C
2: 62 percent / Red-Al / diethyl ether; toluene / 5 h / -20 - 36 °C
3: 1.) methanesulfonyl chloride, triethylamine, 2.) DBU / 1.) CH2Cl2, room temperature, 30 min, 2.) CH2Cl2, room temperature
4: 82 percent / PdCl2(PPh3)2, triethylamine / tetrahydrofuran / 4 h
View Scheme
参考文献
Crousse, Benoit; Mladenova, Margarita; Ducept, Pascal; Alami, Mouad; Linstrumelle, Gerard
Tetrahedron, 1999 , vol. 55, # 14 p. 4353 - 4368
反应条件
1: 1.) methanesulfonyl chloride, triethylamine, 2.) DBU / 1.) CH2Cl2, room temperature, 30 min, 2.) CH2Cl2, room temperature
2: 78 percent / PdCl2(PPh3)2, triethylamine / tetrahydrofuran / 4 h
View Scheme
参考文献
Crousse, Benoit; Mladenova, Margarita; Ducept, Pascal; Alami, Mouad; Linstrumelle, Gerard
Tetrahedron, 1999 , vol. 55, # 14 p. 4353 - 4368
反应条件
1: 79 percent / Red-Al / diethyl ether; toluene / 5 h / -20 - 36 °C
2: 1.) methanesulfonyl chloride, triethylamine, 2.) DBU / 1.) CH2Cl2, room temperature, 30 min, 2.) CH2Cl2, room temperature
3: 78 percent / PdCl2(PPh3)2, triethylamine / tetrahydrofuran / 4 h
View Scheme
参考文献
Crousse, Benoit; Mladenova, Margarita; Ducept, Pascal; Alami, Mouad; Linstrumelle, Gerard
Tetrahedron, 1999 , vol. 55, # 14 p. 4353 - 4368
反应条件
lithium methanolate in methanol
参考文献
Leznoff,C.C.; Hayward,R.J.
Canadian Journal of Chemistry, 1972 , vol. 50, p. 528 - 533
