2-氨基-1-(4-甲氧苯基)-苯乙酮盐酸盐合成路线 （共 30 条）
反应条件
1: With diformylimide sodium salt in acetonitrile T=20 - 70°C; 4 h; 2: With hydrogenchloride in ethanol 1 h; Heating / reflux;
参考文献
PHARMACIA and UPJOHN COMPANY
Patent: WO2004/18428 A1, 2004 ;
Location in patent: Page 356 ;
反应条件
hydrogenchloride; hydrogen; palladium on activated charcoal in ethanol ambient pressure;
参考文献
Sumalekshmy; Henary, Maged M.; Siegel, Nisan; Lawson, PaDreyia V.; Wu, Yonggang; Schmidt, Karin; Bredas, Jean-Luc; Perry, Joseph W.; Fahrni, Christoph J.
Journal of the American Chemical Society, 2007 , vol. 129, # 39 p. 11888 - 11889
反应条件
hydrogenchloride; hydrogen; palladium on activated charcoal in ethanol
参考文献
Nissan Chemical Industries, Ltd.
Patent: EP1552828 A1, 2005 ;
Location in patent: Page/Page column 15-16 ;
反应条件
hydrogen; sulfided platinum on carbon in hydrogenchloride; ethanol T=50°C; P=760 Torr; 22.5 h;
参考文献
Tamura, Rui; Oda, Daihei; Kurokawa, Hiroshi
Tetrahedron Letters, 1986 , vol. 27, # 47 p. 5759 - 5762
反应条件
hydrogenchloride T=120°C; 0.5 h;
参考文献
Yinglin, Han; Hongwen, Hu
Synthesis, 1990 , # 7 p. 615 - 618
反应条件
hydrogenchloride in methanol T=20°C; 1 h;
参考文献
Colpaert, Filip; Mangelinckx, Sven; Denolf, Bram; De Kimpe, Norbert
Journal of Organic Chemistry, 2012 , vol. 77, # 14 p. 6023 - 6032
反应条件
hydrogenchloride; sodium iodide in ethanol
参考文献
Canon Kabushiki Kaisha
Patent: US5217645 A1, 1993 ;
反应条件
hydrogen; palladium on activated charcoal in methanol 2 h;
参考文献
Hall, J. Herbert; Chien, Joseph Yuming; Kauffman, Joel M.; Litak, Peter T.; Adams, Jeffrey K.; et al.
Journal of Heterocyclic Chemistry, 1992 , vol. 29, # 5 p. 1245 - 1273
反应条件
hydrogenchloride in methanol 72 h; Ambient temperature;
参考文献
Hall, J. Herbert; Chien, Joseph Yuming; Kauffman, Joel M.; Litak, Peter T.; Adams, Jeffrey K.; et al.
Journal of Heterocyclic Chemistry, 1992 , vol. 29, # 5 p. 1245 - 1273
反应条件
1: 1.) NaH, 2.) isoamyl nitrite / 1.) t-BuOH, 2.) t-BuOH, 1 h 2: 44 percent / H2 / 10percent Pd/C / methanol / 2 h View Scheme
参考文献
Hall, J. Herbert; Chien, Joseph Yuming; Kauffman, Joel M.; Litak, Peter T.; Adams, Jeffrey K.; et al.
Journal of Heterocyclic Chemistry, 1992 , vol. 29, # 5 p. 1245 - 1273
