3,4-二氢-7-甲氧基-2H-1-苯并吡喃合成路线 （共 10 条）
反应条件
1: With platinum (II) chloride in toluene
T=100°C; 15 h;
2: With hydrogen; palladium on activated charcoal in toluene
T=20°C; 2 h; Title compound not separated from byproducts;
参考文献
Nevado, Cristina; Echavarren, Antonio M.
Chemistry - A European Journal, 2005 , vol. 11, # 10 p. 3155 - 3164
反应条件
pyridine; MeCH=CHCO2Et; nickel dichloride; zinc in N,N-dimethyl-formamide
T=20°C; 2.5 h; Inert atmosphere;
参考文献
Yan, Chang-Song; Peng, Yu; Xu, Xiao-Bo; Wang, Ya-Wen
Chemistry - A European Journal, 2012 , vol. 18, # 19 p. 6039 - 6048
反应条件
triphenylphosphine; diethylazodicarboxylate in tetrahydrofuran
1 h; Ambient temperature;
参考文献
Lal, Kasturi; Ghosh, Subrata; Salomon, Robert G.
Journal of Organic Chemistry, 1987 , vol. 52, # 6 p. 1072 - 1078
反应条件
hexafluoroisopropyl alcohol; bis-[(trifluoroacetoxy)iodo]benzene
T=0 - 20°C;
参考文献
Hamamoto, Hiromi; Hata, Kayoko; Nambu, Hisanori; Shiozaki, Yukiko; Tohma, Hirofumi; Kita, Yasuyuki
Tetrahedron Letters, 2004 , vol. 45, # 11 p. 2293 - 2295
反应条件
hydrogen; palladium on activated charcoal in acetic acid
Ambient temperature;
参考文献
Shiratsuchi; Kawamura; Akashi; Fujii; Ishihama; Uchida
Chemical and Pharmaceutical Bulletin, 1987 , vol. 35, # 2 p. 632 - 641
反应条件
T=150°C; 24 h; Ionic liquid;
参考文献
Hong, Dong Jin; Kim, Dong Wook; Chi, Dae Yoon
Tetrahedron Letters, 2010 , vol. 51, # 1 p. 54 - 56
反应条件
1: potassium carbonate / acetone / 5 h / Inert atmosphere; Reflux
2: pyridine; MeCH=CHCO2Et; nickel dichloride; zinc / N,N-dimethyl-formamide / 2.5 h / 20 °C / Inert atmosphere
View Scheme
参考文献
Yan, Chang-Song; Peng, Yu; Xu, Xiao-Bo; Wang, Ya-Wen
Chemistry - A European Journal, 2012 , vol. 18, # 19 p. 6039 - 6048
反应条件
1: 1.) NaOEt / 1.) EtOH, 10 min, 2.) EtOH, reflux, overnight
2: PCl5, 85percent polyphosphoric acid / 0.5 h
View Scheme
参考文献
Goosen, Andre; Marais, Charles F.; McCleland, Cedric W.; Rinaldi, Fabrizio C.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1995 , # 6 p. 1227 - 1236
反应条件
PPA; phosphorus pentachloride
0.5 h; Title compound not separated from byproducts;
参考文献
Goosen, Andre; Marais, Charles F.; McCleland, Cedric W.; Rinaldi, Fabrizio C.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1995 , # 6 p. 1227 - 1236
反应条件
hydrogen bromide in acetic acid
T=100 - 110°C; Yield given;
参考文献
Shiratsuchi; Kawamura; Akashi; Fujii; Ishihama; Uchida
Chemical and Pharmaceutical Bulletin, 1987 , vol. 35, # 2 p. 632 - 641
