17Alpha-羟基妊娠烯醇酮合成路线 （共 34 条）
反应条件
nickel in ethanol; water Heating / reflux;
参考文献
Boehringer Ingelheim International GmbH
Patent: EP1359154 A1, 2003 ;
Location in patent: Page/Page column 16; 27; 29; 31 ;
反应条件
potassium carbonate in methanol 1 h; Heating;
参考文献
Kasal, Alexander; Pokora, Jenny; Zajicek, Jaroslav
Collection of Czechoslovak Chemical Communications, 1991 , vol. 56, # 6 p. 1340 - 1347
反应条件
hydrogen bromide und anschliessenden Hydrieren an Palladium/CaCO3 in Kaliumacetat enthaltendem Methanol;
参考文献
Ringold et al.
Journal of the American Chemical Society, 1956 , vol. 78, p. 820,823
反应条件
sodium hydroxide; water 3 h; Heating;
参考文献
Joannou; Reeder
Steroids, 1996 , vol. 61, # 1 p. 18 - 21
反应条件
1: 87 percent / ammonium acetate, hydrogen / 5percent Pd/C / methanol / 2 h 2: 83 percent / potasium carbonate / methanol / 1 h / Heating View Scheme
参考文献
Kasal, Alexander; Pokora, Jenny; Zajicek, Jaroslav
Collection of Czechoslovak Chemical Communications, 1991 , vol. 56, # 6 p. 1340 - 1347
反应条件
ammonium acetate; methanol; palladium on activated charcoal Hydrogenation;
参考文献
Ringold et al.
Journal of the American Chemical Society, 1956 , vol. 78, p. 820,823
反应条件
3,4-dihydro-2H-pyran und anschliessend mit Methylmagnesiumbromid;
参考文献
Ruggieri; Ferrari
Journal of the American Chemical Society, 1959 , vol. 81, p. 5725
参考文献
Kasal, Alexander; Pokora, Jenny; Zajicek, Jaroslav
Collection of Czechoslovak Chemical Communications, 1991 , vol. 56, # 6 p. 1340 - 1347
反应条件
1: 92 percent / aq. HClO4 / ethyl acetate / 0.1 h 2: 89 percent / NaBH4 / ethanol / Ambient temperature; other reagent 3: 96 percent / H2O, NaOH / 3 h / Heating View Scheme
参考文献
Joannou; Reeder
Steroids, 1996 , vol. 61, # 1 p. 18 - 21
反应条件
1: 89 percent / NaBH4 / ethanol / Ambient temperature; other reagent 2: 96 percent / H2O, NaOH / 3 h / Heating View Scheme
参考文献
Joannou; Reeder
Steroids, 1996 , vol. 61, # 1 p. 18 - 21
