5-甲基-2-硝基苯甲醚合成路线 （共 55 条）
反应条件
1: N2H4*H2O / Raney-Ni / ethanol
3: aq. NaOH / Heating
4: MeMgI / xylene / Heating
View Scheme
参考文献
Cabiddu,S. et al.
Gazzetta Chimica Italiana, 1969 , vol. 99, p. 397 - 410
参考文献
Brady; Reynolds
Journal of the Chemical Society, 1928 , p. 198,199
Journal of the Chemical Society, 1931 , p. 1274,1277
反应条件
1: 96 percent / hydrogen / 10percent Pd/C / ethanol / 912 Torr
2: 2) MnO2 / 1) CH3CN, 46 h, RT, 2) toluene, RT 24 h and 2 d
View Scheme
参考文献
Knoelker, Hans-Joachim; Bauermeister, Michael
Journal of the Chemical Society, Chemical Communications, 1990 , # 9 p. 664 - 665
反应条件
1: 100 percent / KMnO4, Na2CO3 / H2O / 1.5 h / Heating
2: 95.9 percent / conc. H2SO4 / benzene / 24 h / Heating
3: 74.6 percent / H2 / PtO2 / ethanol / 72 h / 3361.5 Torr / Ambient temperature
View Scheme
参考文献
Ismail, Ibrahim A.; Sharp, Dale E.; Chedekel, Miles R.
Journal of Organic Chemistry, 1980 , vol. 45, # 11 p. 2243 - 2246
反应条件
1: KMnO4 / H2O / Heating
2: SOCl2
View Scheme
参考文献
Julia,M.; Chastrette,F.
Bulletin de la Societe Chimique de France, 1962 , p. 2255 - 2261
反应条件
1: 98 percent / H2 / Pd-C / ethyl acetate / 2585.7 Torr
2: 85 percent / Na2CO3
3: 1) n-BuLi / 1) THF, 25 deg C, 8 h
View Scheme
参考文献
McKenzie, Thomas C.; Hassen, Wesley; Macdonald, Simon J. F.
Tetrahedron Letters, 1987 , vol. 28, # 45 p. 5435 - 5436
反应条件
1: NBS, (PhCO)2O2 / CCl4 / Heating
2: (i) hexamethylenetetramine, (ii) aq. AcOH
View Scheme
参考文献
Julia,M.; Chastrette,F.
Bulletin de la Societe Chimique de France, 1962 , p. 2255 - 2261
反应条件
1: H2 / Pd/C / 3 h / 20 °C
2: 76 percent / Cu(OAc)2 / CH2Cl2 / 2 h / 20 °C
View Scheme
参考文献
Sridharan, Vellaisamy; Martin, Ma. Antonia; Menendez, J. Carlos
Synlett, 2006 , # 15 p. 2375 - 2378
反应条件
bromine in tetrachloromethane
Heating;
参考文献
Julia,M.; Chastrette,F.
Bulletin de la Societe Chimique de France, 1962 , p. 2255 - 2261
反应条件
sodium sulfide; potassium hydroxide; sulfur in ethanol
Heating;
参考文献
Julia,M.; Chastrette,F.
Bulletin de la Societe Chimique de France, 1962 , p. 2255 - 2261
