(2E)-3-(2-羟基-5-甲氧基苯基)丙烯酸合成路线 （共 4 条）
反应条件
sodium hydroxide
2 h; Heating;
参考文献
Chimichi, Stefano; Sio, Francesco De; Donati, Donato; Fina, Giuseppe; Pepino, Roberto; Sarti-Fantoni, Piero
Heterocycles, 1983 , vol. 20, # 2 p. 263 - 267
反应条件
piperidine in pyridine
T=120°C; Knoevenagel Condensation; 1.5 h;
参考文献
Chen, Hongfei; Li, Guoning; Zhan, Peng; Li, Hong; Wang, Shouxun; Liu, Xinyong
MedChemComm, 2014 , vol. 5, # 6 p. 711 - 718
反应条件
1: 80 percent / piperidine
2: 75.2 percent / 1N aq. NaOH / 2 h / Heating
View Scheme
参考文献
Chimichi, Stefano; Sio, Francesco De; Donati, Donato; Fina, Giuseppe; Pepino, Roberto; Sarti-Fantoni, Piero
Heterocycles, 1983 , vol. 20, # 2 p. 263 - 267
反应条件
sodium hydroxide; potassium carbonate
1.) methanol, 3 h; Yield given. Multistep reaction;
参考文献
Dupin, J. F. E.; Chenault, J.
Synthetic Communications, 1985 , vol. 15, # 7 p. 581 - 586
