8-氟-2,3-二氢喹啉-4-酮合成路线 （共 3 条）
反应条件
PPA in (2S)-N-methyl-1-phenylpropan-2-amine hydrate
参考文献
Taisho Pharmaceutical Co. Ltd.
Patent: EP2172453 A1, 2010 ;
Location in patent: Page/Page column 10-11 ;
EP 2172453 A1
反应条件
tert.-butylhydroperoxide; sodium hydroxide in water
参考文献
DowElanco
Patent: US5189210 A1, 1993 ;
反应条件
1: With triethylsilane; trifluoroacetic acid
T=20°C;
2: With sodium hydroxide in water
参考文献
Taisho Pharmaceutical Co. Ltd.
Patent: EP2172453 A1, 2010 ;
Location in patent: Page/Page column 10-11 ;
EP 2172453 A1
