2,3-二氢-1H-茚-1-乙酸合成路线 (共 18 条)
反应条件
hydrogenchloride; mercury; zinc in toluene
144 h; Heating;
参考文献
Lorentzen, Ronald J.; Brewster, James H.; Smith, Howard E.
Journal of the American Chemical Society, 1992 , vol. 114, # 6 p. 2181 - 2187
反应条件
sodium hydroxide in methanol
参考文献
Pharmacia and Upjohn Company
Patent: US5877317 A1, 1999 ;
反应条件
1: polyphosphoric acid / Heating
2: zinc amalgam, aq. HCl / benzene / Heating
View Scheme
参考文献
Pramanik; Mukherjee
Journal of the Indian Chemical Society, 1997 , vol. 74, # 9 p. 734 - 735
反应条件
sodium hydroxide; nickel monoaluminide
参考文献
Dev
Journal of the Indian Chemical Society, 1955 , vol. 32, p. 513,523
反应条件
p-tert-butylbenzoic acid methyl ester; tetra-n-butylammonium tetrafluoroborate in N,N-dimethyl-formamide
T=0°C; Electrolysis;
参考文献
Senboku, Hisanori; Michinishi, Jun-Ya; Hara, Shoji
Synlett, 2011 , # 11 p. 1567 - 1572
反应条件
1: HCO2H
2: aq. KOH / ethanol / Heating
3: H2 / PtO2 / Heating
View Scheme
参考文献
Anderson,A.G. et al.
Journal of Organic Chemistry, 1973 , vol. 38, # 8 p. 1439 - 1444
反应条件
1: Zn, HgCl2, I2 / benzene; diethyl ether / Heating
2: HCO2H
3: aq. KOH / ethanol / Heating
4: H2 / PtO2 / Heating
View Scheme
参考文献
Anderson,A.G. et al.
Journal of Organic Chemistry, 1973 , vol. 38, # 8 p. 1439 - 1444
反应条件
(i) KOH, EtOH, (ii) (decarboxylation); Multistep reaction;
参考文献
Mann,G.
Journal fuer Praktische Chemie (Leipzig), 1963 , vol. 20, p. 210 - 218
反应条件
1: (i) Na, iPrOH, (ii) /BRN= 2081176/
2: (i) KOH, EtOH, (ii) (decarboxylation)
View Scheme
参考文献
Mann,G.
Journal fuer Praktische Chemie (Leipzig), 1963 , vol. 20, p. 210 - 218
反应条件
hydrogen; platinum(IV) oxide
Heating;
参考文献
Anderson,A.G. et al.
Journal of Organic Chemistry, 1973 , vol. 38, # 8 p. 1439 - 1444