2-乙基-1,6-二噁螺[4.4]-壬烷合成路线 （共 18 条）
反应条件
hydrogen; nickel in methanol T=150°C; P=83600 Torr;
参考文献
Kozhich, O. A.; Segal', G. M.; Torgov, I. V.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1982 , vol. 31, # 2 p. 293 - 295
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1982 , # 2 p. 325 - 328
反应条件
hydrogen; Ni(R) in tetrahydrofuran
参考文献
Ireland; Habich
Chemische Berichte, 1981 , vol. 114, # 4 p. 1418 - 1427
反应条件
sodium hydrogencarbonate in water
参考文献
Firmenich S.A.
Patent: US4205084 A1, 1980 ;
反应条件
1.1: nBuLi / tetrahydrofuran / -78 - -30 °C 1.2: 92 percent / BF3*OEt2 / tetrahydrofuran / 1 h / -78 - 20 °C 2.1: 76 percent / H2 / Pd/C / ethanol / 24 h / 20 °C / 760 Torr View Scheme
参考文献
Doubsky, Jan; Streinz, Ludvik; Saman, David; Zednik, Jiri; Koutek, Bohumir
Organic Letters, 2004 , vol. 6, # 26 p. 4909 - 4911
反应条件
1: 67 percent / MCPBA, / methanol / from -5 deg C to room temperature 2: 78 percent / tetrahydrofuran 3: 89 percent / H2 / Ni(R) / tetrahydrofuran View Scheme
参考文献
Ireland; Habich
Chemische Berichte, 1981 , vol. 114, # 4 p. 1418 - 1427
反应条件
1: 78 percent / tetrahydrofuran 2: 89 percent / H2 / Ni(R) / tetrahydrofuran View Scheme
参考文献
Ireland; Habich
Chemische Berichte, 1981 , vol. 114, # 4 p. 1418 - 1427
反应条件
aluminium; mercury dichloride in tetrahydrofuran; water 2 h;
参考文献
Sridharan, Vellaisamy; Vologdin, Nikolay; Virolleaud, Marie-Alice; Bonne, Damien; Bressy, Cyril; Chouraqui, Gaelle; Commeiras, Laurent; Parrain, Jean-Luc; Coquerel, Yoann; Rodriguez, Jean
Synthesis, 2011 , # 13 p. 2085 - 2090
反应条件
aluminium; mercury dichloride in tetrahydrofuran; water 2 h;
参考文献
Sridharan, Vellaisamy; Vologdin, Nikolay; Virolleaud, Marie-Alice; Bonne, Damien; Bressy, Cyril; Chouraqui, Gaelle; Commeiras, Laurent; Parrain, Jean-Luc; Coquerel, Yoann; Rodriguez, Jean
Synthesis, 2011 , # 13 p. 2085 - 2090
反应条件
Raney-Ni W-2 in ethanol; water Heating;
参考文献
Noe, Christian R.; Knollmueller, Max; Dungler, Karin; Gaertner, Peter
Monatshefte fuer Chemie, 1991 , vol. 122, # 3 p. 185 - 194
反应条件
2: 57 percent / hydrogen / Raney nickel / methanol / 150 °C / 83600 Torr 3: 89 percent / pyridine / 12 h / 20 °C 4: 1.) sulfuryl chloride, Et3N, 2.) methaanol, 3.) MeONa / 1.) methylene chloride, 0 deg C, 1 h; 20 deg C, 1 h, 2.) 20 deg c, 2 h, 3.) reflux, 2 h View Scheme
参考文献
Kozhich, O. A.; Segal', G. M.; Torgov, I. V.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1982 , vol. 31, # 2 p. 293 - 295
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1982 , # 2 p. 325 - 328
