3,4,5-三甲氧基苄醇合成路线 （共 102 条）
反应条件
1: H2 / Pd-C / acetic acid / 2206.5 Torr / Ambient temperature 2: aq. H2O2, AcOH, H2SO4 View Scheme
参考文献
Sugihara,H. et al.
Justus Liebigs Annalen der Chemie, 1972 , vol. 763, p. 109 - 120
反应条件
1: H2 / Pd-C / acetic acid / 2206.5 Torr / Ambient temperature 2: aq. H2O2, AcOH View Scheme
参考文献
Sugihara,H. et al.
Justus Liebigs Annalen der Chemie, 1972 , vol. 763, p. 109 - 120
反应条件
1: pyridinium chlorochromate / CH2Cl2 / 3 h 2: sodium acetate / acetic anhydride / Heating 3: NaOH / H2O / Heating 4: hydroxylamine hydrochloride / aq. NaOH / 0.5 h / 60 °C 5: acetic anhydride / 0.08 h / Heating 6: ZnCl2, HCl / diethyl ether / 5 h / 0 °C 7: 2.0 g / aq. potassium persulphate / aq. KOH / Ambient temperature 8: K2CO3 / acetone / 50 h / Heating 9: 1) Na, 2) conc.hydrochloric acid / 1) r.t., 2) heating, 15-20 min. View Scheme
参考文献
Shaw; Srivastava; Jha
Journal of the Indian Chemical Society, 1990 , vol. 67, # 2 p. 144 - 147
反应条件
1: 80 percent / PBr3, triethylamine / CCl4 / 1) 1h, 0 degC 2) 3h, roomtemp. 2: 75 percent / dimethylsulfoxide / Ambient temperature 3: 92 percent / 3N KOH / Heating View Scheme
参考文献
Zheng, Cheng; Guo, Yibing; Meng, Ying; Dou, Sufeng; Shao, Jian; Yang, Yumin
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2013 , vol. 52, # 5 p. 654 - 664
反应条件
1: Lawesson's reagent 2: potassium hydroxide / ethanol / 12 h / 0 - 20 °C 3: m-chloroperoxybenzoic acid; NaHCO3 / CH2Cl2 / 12 h / 20 °C 4: 69 percent / water; potassium hydroxide; carbon tetrachloride / 2-methyl-propan-2-ol / 12 °C / Heating 5: 99 percent / H2 / Pd/C / ethyl acetate View Scheme
参考文献
Robinson, James E.; Taylor, Richard J. K.
Chemical Communications, 2007 , # 16 p. 1617 - 1619
反应条件
1.1: PBr3 / CH2Cl2 / 0.75 h / -5 °C 2.1: 73 percent / 2.17 h / 140 - 180 °C 3.1: 61 percent / NaH; 15-crown-5 / tetrahydrofuran 4.1: Na / tetrahydrofuran / 18 h / 20 °C 4.2: 69 percent / H2O / tetrahydrofuran / 0 °C View Scheme
参考文献
Azzena, Ugo; Dettori, Giovanna; Idini, Maria Vittoria; Pisano, Luisa; Sechi, Grazia
Tetrahedron, 2003 , vol. 59, # 40 p. 7961 - 7966
反应条件
tert.-butylhydroperoxide; V/SiO2 in decane; tert-butyl alcohol T=25°C; 5 h;
参考文献
Rout, Laxmidhar; Nath, Pinku; Punniyamurthy, Tharmalingam
Advanced Synthesis and Catalysis, 2007 , vol. 349, # 6 p. 846 - 848
参考文献
Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Patent: US4239702 A1, 1980 ;
反应条件
in dichloromethane T=25°C; 0.333333 h; reaction with other alcohols; Product distribution;
参考文献
Dess, D. B.; Martin, J. C.
Journal of Organic Chemistry, 1983 , vol. 48, # 22 p. 4155 - 4156
反应条件
1: pyridine / diethyl ether / 2 h / |Reflux; |Inert atmosphere 2: N,N,N',N'-tetramethyl-7,8-dihydro-6H-dipyrido[1,2-a;2',1'-c][1,4] diazepine-2,12-diamine / N,N-dimethyl-formamide / 24 h / |Inert atmosphere; |Glovebox; |UV-irradiation View Scheme
参考文献
Doni, Eswararao; O'Sullivan, Steven; Murphy, John A.
Angewandte Chemie - International Edition, 2013 , vol. 52, # 8 p. 2239 - 2242
Angew. Chem., 2013 , vol. 125, # 8 p. 2295 - 2298,4
