3,4,5-三甲氧基苄氯合成路线 （共 34 条）
反应条件
in water; ethyl acetate; N,N-dimethyl-formamide
反应条件
in acetonitrile T=20°C;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 16 p. 2205 - 2208
反应条件
in acetonitrile Reflux;
参考文献
European Journal of Medicinal Chemistry, , vol. 45, # 1 p. 11 - 18
参考文献
Journal of Organic Chemistry, , vol. 31, p. 1883 - 1887
反应条件
in 1,4-dioxane; water Heating;
参考文献
Bulletin de la Societe Chimique de France, , p. 835 - 843
反应条件
1.1: 80 percent / toluene 2.1: butyllithium / hexane; tetrahydrofuran / 15 - 20 °C 2.2: 54 percent / hexane; tetrahydrofuran / 1 h / 20 °C 3.1: tetrabutylammonium fluoride / tetrahydrofuran / 0.25 h / 20 °C View Scheme
参考文献
Orsini, Fulvia; Pelizzoni, Francesca; Bellini, Barbara; Miglierini, Giuliana
Carbohydrate Research, 1997 , vol. 301, # 3-4 p. 95 - 109
反应条件
1: 5-(chloromethyl)-1,2,3-trimethoxybenzene With tributylphosphine in tetrahydrofuran T=0°C; Wittig reaction; 0.0833333 h; 2: 4-methoxy-benzaldehyde With tetrabutyl ammonium fluoride in tetrahydrofuran T=20°C; Wittig reaction; 16 h; optical yield given as percent dediastereoselective reaction;
参考文献
Fumagalli, Tiziano; Sello, Guido; Orsini, Fulvia
Synthetic Communications, 2009 , vol. 39, # 12 p. 2178 - 2195
反应条件
1: ethanol 2: Hydrolysis.Decarboxylierung View Scheme
参考文献
Cook et al.
Journal of the Chemical Society, 1944 , p. 322,324
反应条件
2: 86 percent / H2, 10percent HCl / 10percent Pd-C / ethanol View Scheme
参考文献
Hashigaki; Kan; Qais; Takeuchi; Yamato
Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 5 p. 1126 - 1131
反应条件
lithium 1. THF, -30 deg C, 2.) THF, 20 deg C, 30 min; Multistep reaction;
参考文献
Muellen, Klaus; Alexander, Juergen; Klabunde, Kay-Uwe; Klaerner, Frank-Gerrit; Lund, Henning; Lund, Torben
Chemische Berichte, 1992 , vol. 125, # 2 p. 505 - 514
