2-氯-1-苯基-1H-吲哚-3-甲醛合成路线 （共 8 条）
反应条件
pyridine; triethylamine; copper diacetate in dichloromethane
T=20°C; 96 h; Molecular sieve;
参考文献
Aventis Pharmaceuticals Inc.
Patent: US2005/54631 A1, 2005 ;
Location in patent: Page/Page column 16 ;
参考文献
Benkli, Kadriye; Demirayak, Seref; Gundogdu-Karaburun, Nalan; Kiraz, Nuri; Iscan, Gokalp; Ucucu, Umit
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2004 , vol. 43, # 1 p. 174 - 179
反应条件
pyridine; trichlorophosphate in chloroform
T=0 - 20°C; Vilsmeier-Haack reaction;
参考文献
Scheiper, Bodo; Matter, Hans; Steinhagen, Henning; Stilz, Ulrich; Boecskei, Zsolt; Fleury, Valerie; McCort, Gary
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 21 p. 6268 - 6272
反应条件
1: Et3N / tetrahydrofuran
2: AlCl3 / 160 - 170 °C
3: POCl3
View Scheme
参考文献
Benkli, Kadriye; Demirayak, Seref; Gundogdu-Karaburun, Nalan; Kiraz, Nuri; Iscan, Gokalp; Ucucu, Umit
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2004 , vol. 43, # 1 p. 174 - 179
反应条件
1: AlCl3 / 160 - 170 °C
2: POCl3
View Scheme
参考文献
Benkli, Kadriye; Demirayak, Seref; Gundogdu-Karaburun, Nalan; Kiraz, Nuri; Iscan, Gokalp; Ucucu, Umit
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2004 , vol. 43, # 1 p. 174 - 179
反应条件
pyridine in acetone
T=20°C; 16 h; Inert atmosphereIrradiation;
参考文献
Wang, Cailin; Zhang, Wei; Lu, Shenci; Wu, Jingfei; Shi, Zongjun
Chemical Communications, 2008 , # 41 p. 5176 - 5178
反应条件
potassium carbonate in N,N-dimethyl-formamide
参考文献
Benkli, Kadriye; Demirayak, Seref; Gundogdu-Karaburun, Nalan; Kiraz, Nuri; Iscan, Gokalp; Ucucu, Umit
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2004 , vol. 43, # 1 p. 174 - 179
反应条件
sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene in 1,4-dioxane; water
T=25°C; 6.5 h;
参考文献
Aventis Pharmaceuticals Inc.
Patent: US2005/54631 A1, 2005 ;
Location in patent: Page/Page column 25-26 ;
