2-溴-4'-(三氟甲基)苯乙酮合成路线 (共 25 条)
反应条件
1: ethanol / |Reflux
2: sodium hydroxide; water / ethanol / 20 °C
3: hydrogenchloride / 1,4-dioxane; water / |Reflux
View Scheme
参考文献
Nitta, Aiko; Fujii, Hideaki; Sakami, Satoshi; Satoh, Mikiya; Nakaki, Junko; Satoh, Shiho; Kumagai, Hiroki; Kawai, Hideki
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 23 p. 7036 - 7040
反应条件
1: in acetone
1 h; Reflux;
2: With perchloric acid in chloroform
6 h; Reflux;
参考文献
Qu, Li; Guo, Yunlong; Luo, Hao; Zhong, Cheng; Yu, Gui; Liu, Yunqi; Qin, Jingui
Chemical Communications, 2012 , vol. 48, # 80 p. 9965 - 9967
参考文献
Bhattacharya,A.K.; Hortmann,A.G.
Journal of Organic Chemistry, 1974 , vol. 39, p. 95 - 99
反应条件
N,N-dimethyl-formamide
参考文献
Tran, Ngoc Diem My; Zard, Samir Z.
Organic and Biomolecular Chemistry, 2014 , vol. 12, # 20 p. 3251 - 3264
反应条件
in isopropyl alcohol
T=27°C; 2 h;
参考文献
Ikemoto, Norihiro; Liu, Jinchu; Brands, Karel M.J.; McNamara, James M.; Reider, Paul J.
Tetrahedron, 2003 , vol. 59, # 8 p. 1317 - 1325