(S)-2-甲基丁基对甲苯磺酸酯合成路线 （共 10 条）
反应条件
pyridine T=4°C; 12 h;
参考文献
Mori, Kenji
Tetrahedron, 2009 , vol. 65, # 19 p. 3900 - 3909
反应条件
pyridine; hydrogenchloride; sodium hydroxide in water; toluene
参考文献
SANYO CHEMICAL INDUSTRIES LTD.
Patent: EP409634 A2, 1991 ;
反应条件
1: p-TsOH*H2O / methanol / 4 h / Heating 2: pyridine / 12 h / 0 - 5 °C View Scheme
参考文献
Mori, Kenji; Wu, Jiang
Liebigs Annalen der Chemie, 1991 , # 3 p. 213 - 217
反应条件
1: NaN3 / dimethylformamide 2: LiAlH4 / diethyl ether View Scheme
参考文献
Kirmse,W.; Arold,H.
Chemische Berichte, 1970 , vol. 103, p. 23 - 26
反应条件
sodium bromide in N,N-dimethyl-formamide T=60°C; 3 h;
参考文献
Odinokov, V. N.; Akhmetova, V. R.; Khasanov, Kh. D.; Abduvakhabov, A. A.; Sul'tanmuratova, V. R.; Tolsikov, G. A.
Journal of Organic Chemistry USSR (English Translation), 1992 , vol. 28, # 6.1 p. 915 - 918
Zhurnal Organicheskoi Khimii, 1992 , vol. 28, # 6 p. 1173 - 1177
反应条件
1: dimethylformamide 2: 40 percent aq. KOH View Scheme
参考文献
Mori, Kenji; Kamada, Atsushi; Kido, Masaru
Liebigs Annalen der Chemie, 1991 , # 8 p. 775 - 781
反应条件
1: 93 percent / dimethylformamide / 2.5 h / 120 °C 2: 99 percent / hydrazine, HCl / ethanol / 4 h / Heating 3: 69 percent / KOH 4: 84 percent / sat. Na2CO3 / diethyl ether / 0.5 h 5: 95 percent / electrolyte Bu4NBF4 / 1.13 h / 10 °C / Pt-anode 6: SnCl4 / H2O / 48 h / Ambient temperature 7: 12 N HCl, DOWEX 50(H+) / 24 h / 100 - 110 °C View Scheme
参考文献
Anteunis, M. J. O.; Callens, R.; Witte, M. De; Reyniers, M. F.; Spiessens, L.
Bulletin des Societes Chimiques Belges, 1987 , vol. 96, # 7 p. 545 - 554
反应条件
1: 67 percent / 2 m NaOEt / ethanol / Heating 2: 1.) KOH, H2O; 2.) conc. H2SO4 / 1.) heating, 2 h; 2.) heating, 4 h; 3: 96 percent / LiAlH4, Et2O / Heating View Scheme
参考文献
Kelly, Stephen M.; Buchecker, Richard
Helvetica Chimica Acta, 1988 , vol. 71, p. 451 - 460
反应条件
sodium iodide in N,N-dimethyl-formamide T=60°C; 1 h;
参考文献
Akasaka, Kazuaki; Tamogami, Shigeyuki; Beeman, Richard W.; Mori, Kenji
Tetrahedron, 2011 , vol. 67, # 1 p. 201 - 209
反应条件
1: 91 percent / CsF / dimethylformamide
2: NaOH / aq. methanol / Saponification
3: NaCl / dimethylsulfoxide / 130 °C
View Scheme
参考文献
Kelly, Stephen M.; Buchecker, Richard
Helvetica Chimica Acta, 1988 , vol. 71, p. 451 - 460
