4-氯-3,5-二硝基苯磺酸钾合成路线 （共 3 条）
反应条件
1: 77 percent / 3 h / Heating 2: PCl5 / CH2Cl2 / 2 h 3: 286 mg / ammonia / methanol / 3 h / 40 °C View Scheme
参考文献
Bhattacharya, Gautam; Herman, Johnathan; Delfin, Dawn; Salem, Manar M.; Barszcz, Todd; Mollet, Mike; Riccio, Guy; Brun, Reto; Werbovetz, Karl A.
Journal of Medicinal Chemistry, 2004 , vol. 47, # 7 p. 1823 - 1832
反应条件
1: With sulfuric acid
T=70°C; 1 h; Inert atmosphere;
2: With sulfuric acid; potassium nitrate
T=130°C; Inert atmosphere;
参考文献
Reddy, Seelam Venkata; Rao, Gangula Mohan; Kumar, Baru Vijaya; Meda, Chandana L.T.; Deora, Girdhar Singh; Kumar, K. Shiva; Parsa, Kishore V.L.; Pal, Manojit
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 7 p. 1952 - 1963
反应条件
1: 76 percent / methanol / 3 h / Heating
2: PCl5 / CH2Cl2 / 2 h
3: 286 mg / pyridine / 3 h / 45 °C
View Scheme
参考文献
Bhattacharya, Gautam; Herman, Johnathan; Delfin, Dawn; Salem, Manar M.; Barszcz, Todd; Mollet, Mike; Riccio, Guy; Brun, Reto; Werbovetz, Karl A.
Journal of Medicinal Chemistry, 2004 , vol. 47, # 7 p. 1823 - 1832
