5-硝基苯-1,3-二甲酰胺合成路线 （共 6 条）
反应条件
1: 86 percent / POCl3 / dimethylformamide / 4 h / 40 - 45 °C 2: 80 percent / hydroxylamine hydrochloride, KOH / bis-(2-hydroxy-ethyl) ether; methanol / 2 h / 25 °C 3: 60 percent / 96 percent H2SO4, 85 percent H3PO4, conc. H2SO4, NaNO2 / 4 h / 0 °C View Scheme
参考文献
Thiel, W.; Mayer, R.; Jauer, E.-A.; Modrow, H.; Dost, H.
Journal fuer Praktische Chemie (Leipzig), 1986 , vol. 328, # 4 p. 497 - 514
反应条件
1: 86 percent / POCl3 / dimethylformamide / 4 h / 40 - 45 °C 2: 80 percent / hydroxylamine hydrochloride, KOH / bis-(2-hydroxy-ethyl) ether; methanol / 2 h / 25 °C View Scheme
参考文献
Thiel, W.; Mayer, R.; Jauer, E.-A.; Modrow, H.; Dost, H.
Journal fuer Praktische Chemie (Leipzig), 1986 , vol. 328, # 4 p. 497 - 514
反应条件
trichlorophosphate in N,N-dimethyl-formamide T=40 - 45°C; 4 h;
参考文献
Thiel, W.; Mayer, R.; Jauer, E.-A.; Modrow, H.; Dost, H.
Journal fuer Praktische Chemie (Leipzig), 1986 , vol. 328, # 4 p. 497 - 514
反应条件
ammonia in water
2.5 h; Cooling;
参考文献
Zahid, Muhammad; Rosspeintner, Arnulf; Angulo, Gonzalo; Grampp, Guenter; Jacques, Patrice; Mansha, Asim
Journal of Photochemistry and Photobiology A: Chemistry, 2011 , vol. 220, # 1 p. 54 - 63
反应条件
1: SOCl2
2: aq. NH3
View Scheme
参考文献
Oshima, Juro; Yoshihara, Toshitada; Tobita, Seiji
Chemical Physics Letters, 2006 , vol. 423, # 4-6 p. 306 - 311
反应条件
1: POCl3
2: Fe; HCl
View Scheme
参考文献
Senear et al.
Journal of Organic Chemistry, 1946 , vol. 11, p. 378,381
