噻吩并[3,2-b]噻吩-2,5-二羧醛合成路线 （共 5 条）
反应条件
potassium hydroxide; iodine 1.) methylene dichloride, 2 h, 2.) abs. toluene, reflux, 6 h; Yield given. Multistep reaction;
参考文献
Kossmehl, Gerhard; Budwill, Detlev
Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, 1985 , vol. 40, # 9 p. 1199 - 1213
反应条件
1: thieno[3,2-b]thiophene With n-butyllithium in diethyl ether; hexane
T=0 - 20°C; 2 h;
2: N,N-dimethyl-formamide in diethyl ether; hexane
T=20°C;
参考文献
Samsung Electronics Co., Ltd.
Patent: EP1932847 A1, 2008 ;
Location in patent: Page/Page column 8-9 ;
反应条件
1: thieno[3,2-b]thiophene With n-butyllithium in tetrahydrofuran
T=0°C; 0.5 h; Inert atmosphere;
2: N-methyl-N-formyl-aniline in tetrahydrofuran
2 h; Inert atmosphere;
参考文献
Ito, Hiroki; Yamamoto, Tatsuya; Yoshimoto, Noriyuki; Tsushima, Noboru; Muraoka, Hiroki; Ogawa, Satoshi
Heteroatom Chemistry, 2013 , vol. 24, # 1 p. 25 - 35
反应条件
1.1: NaBH4 / methanol; CH2Cl2 / 3 h / 20 °C
2.1: 0.30 g / aq. HCl / methanol; CH2Cl2 / 0.5 h / 20 °C
3.1: n-BuLi / hexane; diethyl ether / 0.25 h / -15 °C
3.2: 50 percent / hexane; diethyl ether / 20 °C
View Scheme
参考文献
Leriche, Philippe; Raimundo, Jean-Manuel; Turbiez, Mathieu; Monroche, Vincent; Allain, Magali; Sauvage, Francois-Xavier; Roncali, Jean; Frere, Pierre; Skabara, Peter J.
Journal of Materials Chemistry, 2003 , vol. 13, # 6 p. 1324 - 1332
反应条件
1.1: SOCl2 / diethyl ether / 4 h / Heating
2.1: 1.80 g / AlCl3 / 1,2-dichloro-ethane / 18 h / Heating
3.1: NaBH4 / methanol; CH2Cl2 / 3 h / 20 °C
4.1: 0.30 g / aq. HCl / methanol; CH2Cl2 / 0.5 h / 20 °C
5.1: n-BuLi / hexane; diethyl ether / 0.25 h / -15 °C
5.2: 50 percent / hexane; diethyl ether / 20 °C
View Scheme
参考文献
Leriche, Philippe; Raimundo, Jean-Manuel; Turbiez, Mathieu; Monroche, Vincent; Allain, Magali; Sauvage, Francois-Xavier; Roncali, Jean; Frere, Pierre; Skabara, Peter J.
Journal of Materials Chemistry, 2003 , vol. 13, # 6 p. 1324 - 1332
