5-氮杂三环(8.2.2.24,7)十六碳-4,6,10,12,13,15-己烯合成路线 （共 7 条）
反应条件
phosphorous acid trimethyl ester
18 h; Ambient temperatureIrradiation;
参考文献
Kramer, Joshua J. P.; Nieger, Martin; Braese, Stefan
European Journal of Organic Chemistry, 2013 , # 3 p. 541 - 549
反应条件
1: SOCl2 / 8 h / Heating
2: 2 h / Heating
3: 67 percent / NaBH4, CaCl2 / ethanol / 16 h / Ambient temperature
4: HBr / acetic acid / 144 h / Ambient temperature
5: 62 percent / t-BuOK, Cs2CO3 / aq. ethanol / 16 h / Heating
6: 84 percent / P(OMe)3 / 18 h / Ambient temperature; Irradiation
View Scheme
参考文献
Woersdoerfer, Udo; Voegtle, Fritz; Nieger, Martin; Waletzke, Mirko; Grimme, Stefan; Glorius, Frank; Pfaltz, Andreas
Synthesis, 1999 , # 4 p. 597 - 602
反应条件
1: HBr / acetic acid / 144 h / Ambient temperature
2: 62 percent / t-BuOK, Cs2CO3 / aq. ethanol / 16 h / Heating
3: 84 percent / P(OMe)3 / 18 h / Ambient temperature; Irradiation
View Scheme
参考文献
Woersdoerfer, Udo; Voegtle, Fritz; Nieger, Martin; Waletzke, Mirko; Grimme, Stefan; Glorius, Frank; Pfaltz, Andreas
Synthesis, 1999 , # 4 p. 597 - 602
反应条件
1: 62 percent / t-BuOK, Cs2CO3 / aq. ethanol / 16 h / Heating
2: 84 percent / P(OMe)3 / 18 h / Ambient temperature; Irradiation
View Scheme
参考文献
Woersdoerfer, Udo; Voegtle, Fritz; Nieger, Martin; Waletzke, Mirko; Grimme, Stefan; Glorius, Frank; Pfaltz, Andreas
Synthesis, 1999 , # 4 p. 597 - 602
反应条件
1: sodium tetrahydroborate / ethanol / 18 h / 0 - 20 °C / |Reflux
2: hydrogen bromide / acetic acid / 144 h / 0 - 20 °C
3: caesium carbonate; potassium tert-butylate / ethanol; water / 18 h / 20 °C / |Reflux
4: phosphorous acid trimethyl ester / 12 h / 20 °C / |Photolysis
View Scheme
参考文献
Kramer, Joshua J. P.; Nieger, Martin; Braese, Stefan
European Journal of Organic Chemistry, 2013 , # 3 p. 541 - 549
反应条件
1: 2 h / Heating
2: 67 percent / NaBH4, CaCl2 / ethanol / 16 h / Ambient temperature
3: HBr / acetic acid / 144 h / Ambient temperature
4: 62 percent / t-BuOK, Cs2CO3 / aq. ethanol / 16 h / Heating
5: 84 percent / P(OMe)3 / 18 h / Ambient temperature; Irradiation
View Scheme
参考文献
Woersdoerfer, Udo; Voegtle, Fritz; Nieger, Martin; Waletzke, Mirko; Grimme, Stefan; Glorius, Frank; Pfaltz, Andreas
Synthesis, 1999 , # 4 p. 597 - 602
反应条件
1: 67 percent / NaBH4, CaCl2 / ethanol / 16 h / Ambient temperature
2: HBr / acetic acid / 144 h / Ambient temperature
3: 62 percent / t-BuOK, Cs2CO3 / aq. ethanol / 16 h / Heating
4: 84 percent / P(OMe)3 / 18 h / Ambient temperature; Irradiation
View Scheme
参考文献
Woersdoerfer, Udo; Voegtle, Fritz; Nieger, Martin; Waletzke, Mirko; Grimme, Stefan; Glorius, Frank; Pfaltz, Andreas
Synthesis, 1999 , # 4 p. 597 - 602
