(3E)-3,7-二甲基辛-1,3,6-三烯合成路线 （共 23 条）
反应条件
1.) Mg, THF, B(OBu)3, reflux 1.5h 2.) alkaline H2O2 solution; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Moiseenkov, Alexander M.; Czeskis, Boris A.; Semenovsky, Alexei V.
Tetrahedron Letters, 1980 , vol. 21, p. 853 - 856
反应条件
1.) Mg, THF, B(OBu)3, reflux 1.5h 2.) alkaline H2O2 solution; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Moiseenkov, Alexander M.; Czeskis, Boris A.; Semenovsky, Alexei V.
Tetrahedron Letters, 1980 , vol. 21, p. 853 - 856
反应条件
dilithium tetrachlorocuprate in tetrahydrofuran; ethylene glycol dimethyl ether
T=0 - 20°C; Grignard reaction; 18.75 h; optical yield given as percent de;
参考文献
Yildizhan, Selma; Schulz, Stefan
Synlett, 2011 , # 19 art. no. B08311ST, p. 2831 - 2833
反应条件
in pyridine
T=125°C; 7 h;
参考文献
Cong, Huan; Becker, Clinton F.; Elliott, Sean J.; Grinstaff, Mark W.; Porco Jr., John A.
Journal of the American Chemical Society, 2010 , vol. 132, # 21 p. 7514 - 7518
反应条件
sesquiterpene synthases Cop4 from Coprinus cinereus in terpene synthase buffer
T=25°C; 18 h; Enzymatic reaction;
参考文献
Lopez-Gallego, Fernando; Agger, Sean A.; Abate-Pella, Daniel; Distefano, Mark D.; Schmidt-Dannert, Claudia
ChemBioChem, 2010 , vol. 11, # 8 p. 1093 - 1106
反应条件
germacrene A synthase from Nostoc sp. PCC7120 (NS1) in terpene synthase buffer
T=25°C; 18 h; Enzymatic reaction;
参考文献
Lopez-Gallego, Fernando; Agger, Sean A.; Abate-Pella, Daniel; Distefano, Mark D.; Schmidt-Dannert, Claudia
ChemBioChem, 2010 , vol. 11, # 8 p. 1093 - 1106
反应条件
triethylamine in hexane
T=25°C; 6 h; Irradiation; Yield given. Yields of byproduct given;
参考文献
Saplay, K. M.; Damodaran, N. P.; Dev, Sukh
Tetrahedron, 1983 , vol. 39, # 48 p. 2999 - 3004
反应条件
sesquiterpene synthases Cop6 from Coprinus cinereus in terpene synthase buffer
T=25°C; 18 h; Enzymatic reaction;
参考文献
Lopez-Gallego, Fernando; Agger, Sean A.; Abate-Pella, Daniel; Distefano, Mark D.; Schmidt-Dannert, Claudia
ChemBioChem, 2010 , vol. 11, # 8 p. 1093 - 1106
反应条件
tetrakis(triphenylphosphine) palladium(0); 2-Propynylzinc bromide in tetrahydrofuran
3 h; Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Matsushita, Hajime; Negishi, Ei-ichi
Journal of Organic Chemistry, 1982 , vol. 47, # 21 p. 4161 - 4165
反应条件
2: 82 percent
3: NaI / acetone / 1 h / 0 - 2 °C
4: triethylamine / hexane / 6 h / 25 °C / Irradiation
View Scheme
参考文献
Saplay, K. M.; Damodaran, N. P.; Dev, Sukh
Tetrahedron, 1983 , vol. 39, # 48 p. 2999 - 3004
