2,2-联噻吩-5-乙醛合成路线 （共 24 条）
反应条件
1: aq. NH2OH*HCl; Na2CO3 / methanol / 6 h / Heating 2: Ac2O / 4 h / Heating View Scheme
参考文献
Ismail, Mohamed A.
Journal of Chemical Research, 2006 , # 11 p. 733 - 737
反应条件
1: hydrazine hydrate; diethylene glycol; potassium hydroxide 2: dimethylformamide; phosphoryl chloride; toluene / anschliessendes Behandeln mit wss. Natriumacetat-Loesung 3: diethylene glycol; hydrazine hydrate; potassium hydroxide View Scheme
参考文献
Lescot et al.
Journal of the Chemical Society, 1959 , p. 3234,3235
反应条件
titanium tetrachloride; zinc 1.) THF, -18 deg C, 0.5 h, 2.) THF, from -18 deg C to reflux, 4 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Nakayama, Juzo; Murabayashi, Shigeru; Hoshino, Masamatsu
Heterocycles, 1986 , vol. 24, # 9 p. 2639 - 2643
反应条件
potassium hydroxide; hydrazine hydrate; diethylene glycol
参考文献
Lescot et al.
Journal of the Chemical Society, 1959 , p. 3234,3235
