1-(2-(3-甲氧基苯基)乙炔)苯合成路线 （共 27 条）
反应条件
copper(l) iodide; ethanolamine; bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran; water
T=60°C; Sonogashira coupling; 26 h;
参考文献
Mohamed Ahmed, Mohamed S.; Sekiguchi, Akitoshi; Masui, Kentaro; Mori, Atsunori
Bulletin of the Chemical Society of Japan, 2005 , vol. 78, # 1 p. 160 - 168
反应条件
copper(l) iodide; potassium carbonate; triphenylphosphine in dimethyl sulfoxide
T=90°C; 24 h; Inert atmosphere;
参考文献
Li, Tingyi; Sun, Peng; Yang, Hailong; Zhu, Yan; Yan, Hong; Lu, Linhua; Mao, Jincheng
Tetrahedron, 2012 , vol. 68, # 32 p. 6413 - 6419
反应条件
caesium carbonate; triphenylphosphine; silver(l) oxide in dichloromethane
T=35°C; 3 h; Inert atmosphere;
参考文献
Nie, Xiaopeng; Liu, Suli; Zong, Yan; Sun, Peipei; Bao, Jianchun
Journal of Organometallic Chemistry, 2011 , vol. 696, # 8 p. 1570 - 1573
反应条件
copper(l) iodide; 8-hydroxy-quinoline; sodium salt of phosphorous acid in ethanol
T=80°C; Suzuki coupling; 24 h;
参考文献
Wang, Shihua; Wang, Min; Wang, Lei; Wang, Bo; Li, Pinhua; Yang, Jin
Tetrahedron, 2011 , vol. 67, # 26 p. 4800 - 4806
反应条件
XPhos-SO3Na; dichloro bis(acetonitrile) palladium(II); caesium carbonate in water; acetonitrile
T=100°C; Sonogashira coupling; 12 h;
参考文献
Anderson, Kevin W.; Buchwald, Stephen L.
Angewandte Chemie - International Edition, 2005 , vol. 44, # 38 p. 6173 - 6177
反应条件
copper(l) iodide; palladium(II) complex in various solvent(s)
T=80°C; Sonogashira coupling; 0.25 h; Product distribution; Further Variations:TemperaturesSolventsReagents;
参考文献
Arques, Antonio; Aunon, David; Molina, Pedro
Tetrahedron Letters, 2004 , vol. 45, # 22 p. 4337 - 4340
反应条件
tert.-butylnitrite; trifuran-2-yl-phosphane; palladium diacetate; acetic acid in dimethyl sulfoxide
T=20 - 32°C; Sonogashira coupling; 16 h; Inert atmosphere;
参考文献
Wu, Xiao-Feng; Neumann, Helfried; Beller, Matthias
Chemical Communications, 2011 , vol. 47, # 28 p. 7959 - 7961
反应条件
triethylamine; bis-triphenylphosphine-palladium(II) chloride in N,N-dimethyl-formamide
T=90°C; 12 h;
参考文献
Chen, Qing-Yun; Yang, Zhen-Yu
Tetrahedron Letters, 1986 , vol. 27, # 10 p. 1171 - 1174
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; tetra-(n-butyl)ammonium iodide; diethylamine in acetonitrile
T=20°C; Sonogashira coupling; 2 h; Inert atmosphere;
参考文献
Fabrizi, Giancarlo; Goggiamani, Antonella; Sferrazza, Alessio; Cacchi, Sandro
Angewandte Chemie - International Edition, 2010 , vol. 49, # 24 p. 4067 - 4070
反应条件
1: With tris(dibenzylideneacetone)dipalladium(0) chloroform complex; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene; lithium chloride; silver(l) oxide in N,N-dimethyl-formamide
T=70°C; 3 h; Inert atmosphere;
2: Sonogashira coupling;
参考文献
Kim, Hyunseok; Lee, Phil Ho
Advanced Synthesis and Catalysis, 2009 , vol. 351, # 17 p. 2827 - 2832
