5-甲基-1,3,4-噁二唑-2-羧酸乙酯合成路线 （共 6 条）
反应条件
triethylamine; p-toluenesulfonyl chloride in dichloromethane T=20°C; 8 h;
参考文献
CONCERT PHARMACEUTICALS, INC.
Patent: US2009/35324 A1, 2009 ;
Location in patent: Page/Page column 12 ;
反应条件
in xylene 2 h; Heating;
参考文献
Ogilvie, William; Rank, Werner
Canadian Journal of Chemistry, 1987 , vol. 65, p. 166 - 169
反应条件
in xylene 1 h; Heating;
参考文献
Ogilvie, William; Rank, Werner
Canadian Journal of Chemistry, 1987 , vol. 65, p. 166 - 169
反应条件
anhydrous potassium trimethylsilanolate in diethyl ether T=20°C;
参考文献
CONCERT PHARMACEUTICALS, INC.
Patent: US2009/35324 A1, 2009 ;
Location in patent: Page/Page column 12 ;
反应条件
diisobutylaluminium hydride in dichloromethane
T=-78°C;
参考文献
AVEXA LIMITED
Patent: WO2007/124546 A1, 2007 ;
Location in patent: Page/Page column 60 ;
反应条件
hydrazine hydrate in methanol; diethyl ether
Ambient temperature;
参考文献
Dost, J.; Heschel, M.; Stein, J.
Journal fuer Praktische Chemie (Leipzig), 1985 , vol. 327, # 1 p. 109 - 116
