2,4,6-三氯嘧啶合成路线

参考文献

Chambers, Richard D.; Holmes, Thomas F.; Korn, Stewart R.; Standford, Graham
Journal of the Chemical Society, Chemical Communications, 1993 , # 10 p. 855 - 856

3764-01-02,4,6-三氯嘧啶

3833-57-62,4-二氯-6-氟嘧啶+

3824-45-1+

696-82-22,4,6-三氟嘧啶

参考文献

Hitzke,J.
Journal of Fluorine Chemistry, 1981 , vol. 17, p. 385 - 402

3764-01-02,4,6-三氯嘧啶+

109-89-7二乙胺

10244-23-2

参考文献

Papanikos, Alexandra; Eklund, John; Jackson, W. Roy; Kenche, Vijaya B.; Campi, Eva M.; Robertson, Alan D.; Jarrott, Bevyn; Beart, Philip M.; Munro, Fiona E.; Callaway, Jennifer K.
Australian Journal of Chemistry, 2002 , vol. 55, # 3 p. 205 - 212

3764-01-02,4,6-三氯嘧啶+

67-63-0异丙醇

参考文献

Bello, Angelica M.; Bende, Tanushree; Wei, Lianhu; Wang, Xiaoyang; Majchrzak-Kita, Beata; Fish, Eleanor N.; Kotra, Lakshmi P.
Journal of Medicinal Chemistry, 2008 , vol. 51, # 9 p. 2734 - 2743

参考文献

Bayer Aktiengesellschaft
Patent: US4627872 A1, 1986 ;

123-75-1四氢吡咯+

3764-01-02,4,6-三氯嘧啶

参考文献

Sagi, Vasudeva Naidu; Liu, Tianyu; Lu, Xiaoying; Bartfai, Tamas; Roberts, Edward
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 23 p. 7210 - 7215

123-75-1四氢吡咯+

3764-01-02,4,6-三氯嘧啶

154117-91-64,6-二氯-2-(1-吡咯烷基)嘧啶

参考文献

Richter Gedeon Vegyeszeti Gyar Rt.
Patent: US5510345 A1, 1996 ;

110-91-8吗啉+

3764-01-02,4,6-三氯嘧啶

10397-13-44-(4,6-二氯-2-嘧啶基)吗啉+

52127-83-04-(2,6-二氯-4-嘧啶)吗啉

参考文献

WO2008/125835 A1, ;

Referential example 11 ;
WO 2008/125835 A1

110-91-8吗啉+

3764-01-02,4,6-三氯嘧啶

10397-13-44-(4,6-二氯-2-嘧啶基)吗啉

参考文献

NOVARTIS AG; CARAVATTI, Giorgio; FAIRHURST, Robin Alec; FURET, Pascal; STAUFFER, Frederic; SEILER, Frank Hans; MCCARTHY, Clive; RUEEGER, Heinrich
Patent: US2013/225574 A1, 2013 ;
Location in patent: Paragraph 0502; 0503 ;

3764-01-02,4,6-三氯嘧啶+

74-89-5甲胺

10397-15-64,6-二氯-N-甲基嘧啶-2-胺+

32998-03-12,6-二氯-n-甲基-4-嘧啶胺

参考文献

Nucleosides and Nucleotides, , vol. 13, # 8 p. 1769 - 1777