1: acetoacetic acid tert-butyl ester With n-butyllithium; sodium hydride in tetrahydrofuran; hexane; paraffin oil T=0 - 25°C; Inert atmosphere; 2: 3-lt;3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-ylgt;-2(E)-propenal in tetrahydrofuran; hexane; paraffin oil T=0°C; Inert atmosphere;

hydrogenchloride; diisopropylamine in tetrahydrofuran; n-butyllithium; hexane

1: acetoacetic acid tert-butyl ester With n-butyllithium; sodium hydride in tetrahydrofuran; hexane; paraffin oil T=0 - 25°C; Inert atmosphere; 2: 3-lt;3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-ylgt;-2(E)-propenal in tetrahydrofuran; hexane; paraffin oil T=0°C; Inert atmosphere; 3: With water T=0°C; Temperature;