反应条件
1: 2,4-dichlorophenol, copper / 24 h / 120 - 125 °C
2: sulfur / 24 h / Heating
3: KOH / methanol / 72 h / Heating
4: thionyl chloride / 2 h / 100 °C
5: diethyl ether / Ambient temperature
6: AgNO3, NH4OH / dioxane / 16 h / Heating
7: aq. NaOH / 2-ethoxy-ethanol / 16 h / Heating
View Scheme
参考文献
Atkinson, David C.; Godfrey, Keith E.; Meek, Bernard; Saville, John F.; Stillings, Michael R.
Journal of Medicinal Chemistry, 1983 , vol. 26, # 10 p. 1353 - 1360