2,4-二羟基-6-甲基吡啶合成路线 （共 34 条）
反应条件
1: With sulfuric acid T=130°C; 2 h; 2: With ammonia in water T=100°C; 7 h;
参考文献
WO2006/35967 A1, ;
Page/Page column 71 ;
WO 2006/035967 A1
反应条件
in benzene T=20°C; Molecular sieve;
参考文献
WO2011/22692 A2, ;
Page/Page column 22 ;
WO 2011/022692 A2
反应条件
hydrogenchloride T=195°C;
参考文献
Recueil des Travaux Chimiques des Pays-Bas, , vol. 68, p. 1013,1024
参考文献
Journal of the Chemical Society, , vol. 67, p. 408
反应条件
1: alcohol 2: hydriodic acid View Scheme
参考文献
Journal of the Chemical Society, , vol. 67, p. 408
反应条件
1: phosphorus oxychloride / 120 °C 2: alcohol 3: hydriodic acid View Scheme
参考文献
Journal of the Chemical Society, , vol. 67, p. 408
反应条件
nitric acid; sodium nitrite in acetic acid T=20°C; 0.5 h;
参考文献
Stadlbauer; Fiala; Fischer; Hojas
Journal of Heterocyclic Chemistry, 2000 , vol. 37, # 5 p. 1253 - 1256
反应条件
1: phosphorus oxychloride / 120 °C 2: alcohol 3: hydriodic acid View Scheme
参考文献
Sedgwick; Collie
Journal of the Chemical Society, 1895 , vol. 67, p. 408
反应条件
trichlorophosphate T=140°C; 4 h;
参考文献
Dahlgren, Markus K.; Garcia, Alvaro Baeza; Hare, Alissa A.; Tirado-Rives, Julian; Leng, Lin; Bucala, Richard; Jorgensen, William L.
Journal of Medicinal Chemistry, 2012 , vol. 55, # 22 p. 10148 - 10159
反应条件
phosphorus pentachloride; trichlorophosphate T=130°C;
参考文献
Collie; Myers
Journal of the Chemical Society, 1892 , vol. 61, p. 726
