2,3,5,6-四甲基吡啶合成路线 （共 15 条）
反应条件
1: aqueous KMnO4 2: 180 - 195 °C View Scheme
参考文献
Oparina
Zhurnal Obshchei Khimii, 1949 , vol. 19, p. 1351
Chem.Abstr., 1950 , vol. 44, p. 1108
反应条件
1: 2,3,5-trimethyl-pyridine With n-butyllithium in diethyl ether; hexane
1.16667 h; Inert atmosphere;
2: methyl iodide in diethyl ether; hexane
T=-78 - 20°C; Inert atmosphere;
参考文献
Verdia, Pedro; Gonzalez, Emilio J.; Rodriguez-Cabo, Borja; Tojo, Emilia
Green Chemistry, 2011 , vol. 13, # 10 p. 2768 - 2776
参考文献
Koei Chemical Co., Ltd.
Patent: US4658032 A1, 1987 ;
反应条件
aluminum oxide; ammonia; water
T=350°C;
参考文献
Oparina
Zhurnal Obshchei Khimii, 1949 , vol. 19, p. 1351
Chem.Abstr., 1950 , vol. 44, p. 1108
反应条件
aluminum oxide; ammonia; water; acetone
T=340°C;
参考文献
Oparina
Chemische Berichte, 1931 , vol. 64, p. 574
Zhurnal Obshchei Khimii, 1949 , vol. 19, p. 1352
Chem.Abstr., 1950 , p. 1108
反应条件
1: 2,3,5-trimethyl-pyridine; n-butyllithium in diethyl ether; hexane
1.16667 h; Inert atmosphere;
2: methyl iodide in diethyl ether; hexane
T=-78 - 20°C; Inert atmosphere;
参考文献
Verdia, Pedro; Gonzalez, Emilio J.; Rodriguez-Cabo, Borja; Tojo, Emilia
Green Chemistry, 2011 , vol. 13, # 10 p. 2768 - 2776
反应条件
methanol; palladium on activated charcoal; Lindlar's catalyst
Hydrogenation;
参考文献
Tsuda et al.
Pharmaceutical Bulletin, 1953 , vol. 1, p. 122,125
反应条件
1: thionyl chloride
2: palladium/calcium carbonate; methanol / Hydrogenation
View Scheme
参考文献
Tsuda et al.
Pharmaceutical Bulletin, 1953 , vol. 1, p. 122,125
反应条件
1: lithium alanate; diethyl ether
2: thionyl chloride
3: palladium/calcium carbonate; methanol / Hydrogenation
View Scheme
参考文献
Tsuda et al.
Pharmaceutical Bulletin, 1953 , vol. 1, p. 122,125
反应条件
perchloric acid
Erhitzen des Reaktionsprodukts mit wss. Essigsaeure und Ammoniumacetat;
参考文献
Praill; Whitear
Proceedings of the Chemical Society, London, 1959 , p. 312
Journal of the Chemical Society, 1961 , p. 3573,3578
