1-[3,5-二(叔丁基)-2-羟基苯基]-1-乙酮合成路线 （共 14 条）
反应条件
1.1: DMF / SOCl2 / 12 h / 20 °C
1.2: 93 percent / dimethylaminopyridine / pyridine; H2O / 20 °C
2.1: 92 percent / tetrahydrofuran / 2 h / 20 °C
View Scheme
参考文献
Jimenez, Claudio A.; Belmar, Julio B.
Synthetic Communications, 2007 , vol. 37, # 14 p. 2391 - 2397
反应条件
1.1: 75 percent / aq. KOH / methanol / 4 h / Heating
2.1: DMF / SOCl2 / 12 h / 20 °C
2.2: 93 percent / dimethylaminopyridine / pyridine; H2O / 20 °C
3.1: 92 percent / tetrahydrofuran / 2 h / 20 °C
View Scheme
参考文献
Jimenez, Claudio A.; Belmar, Julio B.
Synthetic Communications, 2007 , vol. 37, # 14 p. 2391 - 2397
反应条件
1.1: 94 percent / sulfuric acid / methanol / 5 h / 20 °C
2.1: 75 percent / aq. KOH / methanol / 4 h / Heating
3.1: DMF / SOCl2 / 12 h / 20 °C
3.2: 93 percent / dimethylaminopyridine / pyridine; H2O / 20 °C
4.1: 92 percent / tetrahydrofuran / 2 h / 20 °C
View Scheme
参考文献
Jimenez, Claudio A.; Belmar, Julio B.
Synthetic Communications, 2007 , vol. 37, # 14 p. 2391 - 2397
反应条件
1: 1.) AcOH, 2.) H3O+
2: 1.) Et2O
3: 31 percent / CrO3
View Scheme
参考文献
Hayashi; Tanaka; Oguni
Tetrahedron Asymmetry, 1995 , vol. 6, # 8 p. 1833 - 1836
