in toluene a) -78 deg C, b) r.t., 15-20 h;

1: Methyltriphenylphosphonium bromide With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 1 h; Inert atmosphere; 2: (iodomethyl)trimethylsilane in tetrahydrofuran; hexane T=-78 - 0°C; Inert atmosphere;

n-butyllithium 1) THF, hexane, RT, 1 h, 2) THF, hexane, RT, 1 h; Yield given. Multistep reaction;

1: 95 percent / Na<N(SiMe3)2> / diethyl ether / 20 h / Ambient temperature 2: 93 percent / toluene / a) -78 deg C, b) r.t., 15-20 h 3: 99 percent / Na<N(SiMe3)2> / diethyl ether / 20 h / Ambient temperature View Scheme

sodium hexamethyldisilazane in diethyl ether 20 h; Ambient temperature;