1-(3-羧苯基)-2-硫脲合成路线 （共 8 条）
反应条件
sodium methylate in methanol T=20°C; 1 h;
参考文献
SAINT LOUIS UNIVERSITY; RUMINSKI, Peter; GRIGGS, David
Patent: WO2014/15054 A1, 2014 ;
Location in patent: Page/Page column 161 ;
反应条件
ammonia in ethanol T=20°C; 1 h;
参考文献
KINETEK PHARMACEUTICALS, INC.
Patent: WO2004/11460 A2, 2004 ;
Location in patent: Page 59 ;
WO 2004/011460 A2
反应条件
1: acetone / Ambient temperature 2: 2.0 N aq. NaOH / tetrahydrofuran / 3 h / Heating View Scheme
参考文献
SAINT LOUIS UNIVERSITY; RUMINSKI, Peter; GRIGGS, David
Patent: WO2014/15054 A1, 2014 ;
参考文献
Traube,I.
Chemische Berichte, 1882 , vol. 15, p. 2113,2117
参考文献
Arzruni
Chemische Berichte, 1871 , vol. 4, p. 407
反应条件
1: ammoniacal silver 2: diluted hydrochloric acid View Scheme
参考文献
Traube,I.
Chemische Berichte, 1882 , vol. 15, p. 2113,2117
反应条件
bromine in chloroform T=20°C; 63 h; Heating / reflux;
参考文献
KINETEK PHARMACEUTICALS, INC.
Patent: WO2004/11460 A2, 2004 ;
Location in patent: Page 59 ;
WO 2004/011460 A2
反应条件
1: ethanol / 5 h / |Reflux
2: ammonium hydroxide / 3 h / |Reflux
View Scheme
参考文献
SAINT LOUIS UNIVERSITY; RUMINSKI, Peter; GRIGGS, David
Patent: WO2014/15054 A1, 2014 ;
